SCHEMBL483755

SCHEMBL483755

O=CCc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.59
TSHR P16473 1/20 0.55
IDO1 P14902 4/20 0.53
CYP2C19 P33261 3/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C9 P11712 1/20 0.53
POLB P06746 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CHRM2 P08172 1/20 0.52
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ATM Q13315 1/20 0.49
KCNJ1 P48048 1/20 0.48
KCNH2 Q12809 1/20 0.48
ACHE P22303 1/20 0.48
HSD17B10 Q99714 1/20 0.48
AKR1C3 P42330 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9528716 1.00 LOXL2 (0.59) LOXL2TSHRIDO1CYP2C19CYP1A2
SCHEMBL40826 0.89 HSPB1 (0.58) LOXL2TSHRIDO1CYP2C19CYP1A2
SCHEMBL28148788 0.83 LOXL2 (0.55) LOXL2TSHRIDO1CYP2C19CYP1A2
SCHEMBL27765240 0.83 LOXL2 (0.61) LOXL2TSHRIDO1CYP2C19CYP1A2
SCHEMBL27574845 0.83 LOXL2 (0.55) LOXL2TSHRIDO1CYP2C19CYP1A2
SCHEMBL3633600 0.83 LOXL2 (0.55) LOXL2TSHRIDO1CYP2C19CYP1A2
SCHEMBL7090996 0.83 LOXL2 (0.55) LOXL2TSHRIDO1CYP2C19CYP1A2
SCHEMBL28258180 0.83 LOXL2 (0.55) LOXL2TSHRIDO1CYP2C19CYP1A2
SCHEMBL1169849 0.83 LOXL2 (0.55) LOXL2TSHRIDO1CYP2C19CYP1A2
SCHEMBL27943219 0.82 IDO1 (0.50) LOXL2TSHRIDO1CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 579 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215467-A1 L-THREONINE TRANSALDOLASES AND USES THEREOF UNIVERSITY OF DELAWARE (US) 2025-07-03 US claimed
WO-2023178318-A2 L-THREONINE TRANSALDOLASES AND USES THEREOF KUNJAPUR ADITYA (US) 2023-09-21 WO claimed
CN-109651290-B Preparation method of mirabegron 安徽省庆云医药股份有限公司 2022-04-01 CN claimed
CN-109651290-A A kind of preparation method of Mirabegron 安徽省庆云医药股份有限公司 2019-04-19 CN claimed
WO-2018229261-A1 COMBINATION MEDICAMENT COMPRISING A PRODRUG AND INHALABLE CATALYST ETH Zürich (CH) 2018-12-20 WO claimed
CN-103265457-B A kind of synthetic method of (R)-4-aminophenethyl-(2-hydroxyl-2-styroyl)-t-butyl carbamate SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) 2015-08-19 CN claimed
CN-103232368-B A kind of synthetic method of (R)-4-nitrophenethyl-(2-hydroxyl-2-styroyl)-t-butyl carbamate SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) 2015-08-12 CN claimed
CN-103265457-A (R)-4-amino phenethyl-(2-hydroxy-2-phenylethyl)-tert-butyl carbamate synthesis method SUZHOU UUGENE BIOPHARMA CO LTD 2013-08-28 CN claimed
CN-103232368-A Synthesizing method of (R)-4-nitrophenethyl-(2-hydroxy-2-phenylethyl)-tert-butyl carbamate SUZHOU UUGENE BIOPHARMA CO LTD 2013-08-07 CN claimed
CN-103193658-A Synthesis method of (R)-2-p-nitrobenzene ethylamine-1-phenethyl alcohol and salt thereof SUZHOU UUGENE BIOPHARMA CO LTD 2013-07-10 CN claimed
US-5656753-A 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them AMERICAN CYANAMID COMPANY (US) 1997-08-12 US claimed
WO-1991018861-A1 2-(HYDROXYMETHYL) ACRYLATE DERIVATIVES AND PROCESS FOR THEIR PREPARATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1991-12-12 WO claimed
EP-4659809-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2025-12-10 EP disclosed
EP-3538539-B1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMA (US) 2025-08-27 EP disclosed
US-12377159-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-08-05 US disclosed
US-20250215467-A1 L-THREONINE TRANSALDOLASES AND USES THEREOF UNIVERSITY OF DELAWARE (US) 2025-07-03 US disclosed
US-4364865-A ANTIBIOTICS CIBA-GEIGY CORPORATION (US) 1982-12-21 US disclosed
US-4191808-A DIPEPTIDE CONTAINING PROLINE AND A PHOTOMETRICALLY DETECTABLE NITROANILINE, PHENYLAZOANILINE OR PHENYLAZONAPHTHYLAMINE GROUP AJINOMOTO CO., INC. (JP) 1980-03-04 US disclosed
US-4119620-A Novel dipeptide derivatives, salts thereof, and method of measuring enzyme activity AJINOMOTO CO., INC. (JP) 1978-10-10 US disclosed
US-4070477-A PENICILLINS CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12377159-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 LOXL2 2310/4885TSHR 809/4885IDO1 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.