Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MYOC | Q99972 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528716 | 0.89 | LOXL2 (0.59) | KMT2AMEN1KCNH2ALDH1A1IDO1 | |
| SCHEMBL483755 | 0.89 | LOXL2 (0.59) | KMT2AMEN1KCNH2ALDH1A1IDO1 | |
| SCHEMBL5737945 | 0.84 | LTA4H (0.53) | KMT2AMEN1MAPTALDH1A1PTGS2 | |
| SCHEMBL2000238 | 0.83 | HSPB1 (0.63) | HSPB1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL9183872 | 0.82 | HSPB1 (0.79) | HSPB1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL11689190 | 0.82 | HSPB1 (0.79) | HSPB1KMT2AMEN1MAPTNPC1 | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL134332 | 0.82 | HSPB1 (0.79) | HSPB1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL2011179 | 0.82 | HSPB1 (0.79) | HSPB1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL11777893 | 0.82 | CHRM2 (0.60) | HSPB1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL7807343 | 0.82 | L3MBTL1 (0.68) | HSPB1KMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006038-A2 | AGENTS AND COMPOUNDS FOR IMAGING AND OTHER APPLICATIONS, AND METHODS OF USE AND SYNTHESIS THEREOF | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-01-12 | — | — | WO | disclosed |