⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211340 | 0.72 | LMNA (0.45) | — | |
| SCHEMBL15516303 | 0.72 | LMNA (0.45) | — | |
| SCHEMBL9252715 | 0.69 | — | — | |
| SCHEMBL1617422 | 0.69 | — | — | |
| SCHEMBL8083497 | 0.69 | — | — | |
| SCHEMBL28006477 | 0.69 | — | — | |
| SCHEMBL6851940 | 0.68 | — | — | |
| SCHEMBL28046675 | 0.67 | LMNA (0.41) | — | |
| SCHEMBL1479730 | 0.67 | LMNA (0.55) | — | |
| SCHEMBL10873549 | 0.65 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456281-B2 | Nucleic acid melting analysis with saturation dyes | IDAHO TECHNOLOGY, INC. | 2008-11-25 | — | — | US | claimed |
| JP-2008510698-A | — | — | 2008-04-10 | — | — | JP | claimed |
| EP-1774047-A2 | NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES | University of Utah Research Foundation (US) | 2007-04-18 | — | — | EP | claimed |
| US-20070020672-A1 | Nucleic acid melting analysis with saturation dyes | IDAHO TECHNOLOGY, INC. (US) | 2007-01-25 | — | — | US | claimed |
| WO-2006121423-A2 | NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2006-11-16 | — | — | WO | claimed |
| US-20050233335-A1 | standard PCR solution with additional saturating double-stranded (ds) DNA binding dye; fluorescence; cyanine dyes | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2005-10-20 | — | — | US | claimed |
| EP-2826867-A1 | Nucleic acid melting analysis with saturation dyes | University of Utah Research Foundation (US) | 2015-01-21 | — | — | EP | disclosed |
| EP-2574678-A1 | Thio-substituted methine dyes | University of Utah Research Foundation (US) | 2013-04-03 | — | — | EP | disclosed |