SCHEMBL4837670

SCHEMBL4837670

CC(C)(C)Oc1cccc(P([N]P(c2cccc(OC(C)(C)C)c2)c2cccc(OC(C)(C)C)c2)c2cccc(OC(C)(C)C)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.37
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PRKDC P78527 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2235524 0.82 KIF11 (0.40) KIF11KDM4EMEN1ALDH1A1HPGD
SCHEMBL2155172 0.79 KIF11 (0.38) KIF11KDM4EMEN1ALDH1A1HPGD
SCHEMBL2154097 0.79 KIF11 (0.38) KIF11KDM4EMEN1ALDH1A1HPGD
SCHEMBL4840730 0.79 ACHE (0.48) ALDH1A1
SCHEMBL4837677 0.78 KIF11 (0.37) KIF11KDM4EMEN1ALDH1A1HPGD
SCHEMBL260934 0.77 KIF11 (0.47) KIF11KDM4EMEN1ALDH1A1HPGD
SCHEMBL4837169 0.76 SLC6A2 (0.34) KIF11
SCHEMBL2154071 0.75 KIF11 (0.38) KIF11KDM4EMEN1ALDH1A1HPGD
SCHEMBL2154003 0.75 KIF11 (0.38) KIF11KDM4EMEN1ALDH1A1HPGD
SCHEMBL4839945 0.74 TP53 (0.52) KDM4EMEN1ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378537-B2 Olefin oligomerization catalysts and methods of using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-05-27 US disclosed
US-20080027188-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-01-31 US disclosed