SCHEMBL260934

SCHEMBL260934

CC(C)(C)Oc1cccc(OC(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.47
RIPK1 Q13546 1/20 0.39
ACHE P22303 1/20 0.37
MEN1 O00255 3/20 0.37
ALDH1A1 P00352 3/20 0.37
KMT2A Q03164 3/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CYP3A4 P08684 3/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MITF O75030 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
GFER P55789 1/20 0.36
NLRP1 Q9C000 1/20 0.36
NOD2 Q9HC29 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678558 0.91 ACHE (0.52) ACHEMEN1ALDH1A1KMT2AKDM4E
SCHEMBL6764359 0.89 KCNH2 (0.44) KIF11CETP
SCHEMBL2092198 0.87 KIF11 (0.43) KIF11RIPK1ACHEMEN1ALDH1A1
SCHEMBL27510359 0.87 KIF11 (0.40) KIF11RIPK1ACHEMEN1ALDH1A1
SCHEMBL1802320 0.85 CYP3A4 (0.53) KIF11ACHEALDH1A1CYP3A4CA2
SCHEMBL7386225 0.85 ACHE (0.58) KIF11ACHEALDH1A1NPSR1GAA
Hydrochloric Acid SCHEMBL27456142 0.85 KIF11 (0.39) KIF11RIPK1MEN1ALDH1A1KMT2A
SCHEMBL13178937 0.85 KIF11 (0.39) KIF11RIPK1MEN1ALDH1A1KMT2A
SCHEMBL22924645 0.85 TP53 (0.55) MEN1ALDH1A1KMT2AKDM4ENPSR1
SCHEMBL1802316 0.84 KIF11 (0.44) KIF11RIPK1ACHEMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109354684-B Process for synthesizing poly (p-phenylene benzobisoxazole) 长江师范学院 2021-01-05 CN claimed
CN-109354684-B Process for synthesizing poly (p-phenylene benzobisoxazole) 长江师范学院 2021-01-05 CN disclosed
US-20200339861-A1 METHOD FOR IMPROVING CEMENT TOUGHNESS SAUDI ARABIAN OIL COMPANY (SA) 2020-10-29 US disclosed
US-10637030-B2 Nonaqueous electrolyte secondary battery insulating porous layer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-04-28 US disclosed
US-20200039125-A1 METHOD FOR MANUFACTURING RESIN MOLDED BODY AND RESIN MOLDED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-02-06 US disclosed
US-10516148-B2 Nonaqueous electrolyte secondary battery insulating porous layer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-12-24 US disclosed
US-20170306147-A1 WEATHERABLE THERMOPLASTIC COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-10-26 US disclosed
US-20170306147-A1 WEATHERABLE THERMOPLASTIC COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-10-26 US disclosed
US-9708465-B2 Color-stable thermoplastic composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-18 US disclosed
US-9708465-B2 Color-stable thermoplastic composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-18 US disclosed
US-20070066740-A1 Annular or tubular shaped articles of novel polymer blends CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed
US-20070066738-A1 Flame retardant polysulfone blends SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-03-22 US disclosed
US-20070065615-A1 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US disclosed
US-20070066737-A1 Flame retardant polymer blends SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-03-22 US disclosed
US-20070027271-A1 WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-02-01 US disclosed
US-7169859-B2 Weatherable, thermostable polymers having improved flow composition GENERAL ELECTRIC COMPANY (US) 2007-01-30 US disclosed
US-6656328-B2 Subjecting a polyhydric alcohol compound having protected hydroxy group(s) to microwave irradiation in presence of basic compound or acid to deprotect the protecting groups of hydroxy group of polyhydric alcohol compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2003-12-02 US disclosed
EP-1298115-A1 PROCESS FOR THE PREPARATION OF POLYHYDRIC ALCOHOLS National Institute of Advanced Industrial Science and Technology (JP) 2003-04-02 EP disclosed
US-20020157939-A1 Process for preparation of polyhydric alcohols NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2002-10-31 US disclosed
US-4125512-A RESORCINOL DONOR, FORMALDEHYDE DONOR, CALCIUM SILICATE, GROUP 2A OR 3A METAL OXIDE BAYER AKTIENGESELLSCHAFT (DE) 1978-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020157939-A1 Process for preparation of polyhydric alcohols ADH1C, ADH1A, ADH5 KIF11 1977/4885RIPK1 3038/4885ACHE 4523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.