SCHEMBL4840730

SCHEMBL4840730

COc1cccc(P([N]P(c2cccc(OC)c2)c2cccc(OC)c2)c2cccc(OC)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.48
CYP3A4 P08684 2/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CHRM5 P08912 1/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR3A P46098 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ENPP2 Q13822 1/20 0.42
TAAR1 Q96RJ0 2/20 0.42
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29635198 0.80 ACHE (0.54) ACHECYP3A4CA1CA2CA7
SCHEMBL197286 0.80 ACHE (0.54) ACHECYP3A4CA1CA2CA7
SCHEMBL4839945 0.79 TP53 (0.52) CYP3A4ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL4841350 0.79 RXRA (0.41) CA2ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL4837670 0.79 KIF11 (0.37) ALDH1A1
Phosphine SCHEMBL6466867 0.78 ACHE (0.52) ACHECYP3A4CA1CA2CA7
SCHEMBL2155304 0.78 ACHE (0.52) ACHECYP3A4CA1CA2CA7
Hydrochloric Acid SCHEMBL5427158 0.78 ACHE (0.52) ACHECYP3A4CA1CA2CA7
SCHEMBL31189339 0.78 ACHE (0.52) ACHECYP3A4CA1CA2CA7
SCHEMBL9420847 0.78 ACHE (0.52) ACHECYP3A4CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378537-B2 Olefin oligomerization catalysts and methods of using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-05-27 US disclosed
US-20080027188-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-01-31 US disclosed