SCHEMBL4839685

SCHEMBL4839685

CC(C)(C)Cc1ccccc1P(NP(c1ccccc1CC(C)(C)C)c1ccccc1CC(C)(C)C)c1ccccc1CC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.42
LMNA P02545 1/20 0.31
CYP2D6 P10635 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4832909 0.77 GABRA1 (0.39) LMNAMEN1KMT2A
SCHEMBL4839680 0.76 RIPK1 (0.42) RIPK1
SCHEMBL6685097 0.75 RIPK1 (0.56) RIPK1LMNACYP2D6
SCHEMBL9718549 0.69 RIPK1 (0.50) RIPK1LMNACYP2D6
SCHEMBL14785290 0.68 RIPK1 (0.46) RIPK1LMNACYP2D6
SCHEMBL4830198 0.68 ALDH1A1 (0.43) KMT2A
SCHEMBL3167835 0.67 RIPK1 (0.48) RIPK1LMNAKMT2A
SCHEMBL6685032 0.67 RIPK1 (0.48) RIPK1CYP2D6
SCHEMBL24048341 0.67 RIPK1 (0.44) RIPK1LMNACYP2D6MEN1KMT2A
SCHEMBL13334563 0.67 SLC6A4 (0.46) RIPK1LMNACYP2D6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378537-B2 Olefin oligomerization catalysts and methods of using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-05-27 US disclosed
US-20080027188-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-01-31 US disclosed