Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.47 |
| ▸ | DRD3 | P35462 | 10/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4842301 | 0.92 | DRD2 (0.54) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL4835143 | 0.92 | DRD2 (0.54) | DRD2DRD3HTR1AKDM4EMAPT | |
| Trifluoroacetic Acid SCHEMBL4844696 | 0.89 | CACNA1G (0.56) | KDM4EMAPTKMT2AMEN1HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL4840800 | 0.88 | CHEK2 (0.45) | DRD3 | |
| Trifluoroacetic Acid SCHEMBL4835114 | 0.88 | DRD2 (0.56) | DRD2DRD3MAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4843197 | 0.88 | TBK1 (0.51) | DRD3KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4841456 | 0.86 | CHEK2 (0.45) | DRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL4842116 | 0.86 | CHEK2 (0.53) | — | |
| Trifluoroacetic Acid SCHEMBL4834798 | 0.85 | CYP4F2 (0.49) | DRD3 | |
| Trifluoroacetic Acid SCHEMBL4840505 | 0.85 | DRD2 (0.55) | DRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | DRD2 3267/4885DRD3 2580/4885HTR1A 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.