Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845148 | 0.92 | TSHR (0.36) | RORCTRPA1TSHRMAPK1MAPT | |
| SCHEMBL4836980 | 0.91 | CA12 (0.40) | RORCTRPA1MMP8MMP3 | |
| SCHEMBL4841609 | 0.89 | TRPA1 (0.36) | RORCTRPA1TSHRMAPK1MAPT | |
| SCHEMBL4832976 | 0.89 | MAPT (0.39) | RORCTRPA1TSHRMAPK1SCN9A | |
| SCHEMBL4842813 | 0.89 | TRPA1 (0.37) | RORCTRPA1MAPK1MAPT | |
| SCHEMBL4833497 | 0.87 | TSHR (0.37) | RORCTRPA1TSHRMAPK1SCN9A | |
| SCHEMBL4841750 | 0.87 | RORC (0.38) | RORCTRPA1MMP8MMP3 | |
| SCHEMBL4843418 | 0.87 | TRPA1 (0.36) | RORCTRPA1TSHRMMP8MMP3 | |
| SCHEMBL4842787 | 0.87 | MAPT (0.40) | RORCTRPA1TSHRMMP8MMP3 | |
| SCHEMBL4842782 | 0.87 | TRPA1 (0.39) | RORCTRPA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | RORC 1777/4885TRPA1 368/4885TSHR 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.