SCHEMBL4841358

SCHEMBL4841358

CC(C)Oc1cccc(P(NP(c2cccc(OC(C)C)c2)c2cccc(OC(C)C)c2)c2cccc(OC(C)C)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
ALDH1A1 P00352 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
KDM4E B2RXH2 3/20 0.40
NSD2 O96028 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
GAA P10253 2/20 0.40
HTT P42858 1/20 0.40
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
LMNA P02545 3/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
KAT6A Q92794 1/20 0.38
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154954 0.79 RXRA (0.46) RXRARXRBALDH1A1SMN1; SMN2KDM4E
SCHEMBL2154565 0.79 RXRA (0.42) RXRARXRBALDH1A1SMN1; SMN2KDM4E
SCHEMBL4840736 0.79 ACHE (0.48) ALDH1A1SMN1; SMN2MEN1KMT2ANPC1
SCHEMBL4841350 0.78 RXRA (0.41) RXRARXRBALDH1A1SMN1; SMN2KDM4E
SCHEMBL2968363 0.77 RXRA (0.53) RXRARXRBALDH1A1SMN1; SMN2KDM4E
SCHEMBL4833413 0.76 ALDH1A3 (0.45) ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL2155034 0.75 RXRA (0.43) RXRARXRBALDH1A1SMN1; SMN2KDM4E
SCHEMBL2155929 0.75 RXRA (0.46) RXRARXRBALDH1A1SMN1; SMN2KDM4E
SCHEMBL4837677 0.74 KIF11 (0.37) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL4839953 0.74 TP53 (0.52) RXRARXRBALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378537-B2 Olefin oligomerization catalysts and methods of using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-05-27 US disclosed
US-20080027188-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-01-31 US disclosed