Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4841397 | 0.99 | MRGPRX4 (0.52) | MRGPRX4NOTUMTHRATHRBS1PR1 | |
| SCHEMBL15662107 | 0.88 | MRGPRX4 (0.54) | MRGPRX4NOTUMTHRATHRBS1PR1 | |
| SCHEMBL25313061 | 0.88 | KDM4E (0.56) | MRGPRX4NOTUMTHRATHRBS1PR1 | |
| SCHEMBL16372433 | 0.86 | MRGPRX4 (0.53) | MRGPRX4NOTUMTHRATHRBS1PR1 | |
| SCHEMBL2018525 | 0.85 | NOTUM (0.56) | MRGPRX4NOTUMTHRATHRBKDM4E | |
| SCHEMBL10088909 | 0.85 | NOTUM (0.56) | MRGPRX4NOTUMTHRATHRBS1PR1 | |
| SCHEMBL27195845 | 0.84 | THRA (0.60) | MRGPRX4NOTUMTHRATHRBKDM4E | |
| SCHEMBL30882489 | 0.83 | MRGPRX4 (0.50) | MRGPRX4NOTUMTHRATHRBS1PR1 | |
| SCHEMBL4841298 | 0.83 | LMNA (0.47) | NOTUMTHRATHRBKDM4EHTT | |
| Hydrochloric Acid SCHEMBL4841289 | 0.82 | BCL9 (0.47) | NOTUMTHRATHRBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | MRGPRX4 675/4885NOTUM 1464/4885THRA 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.