SCHEMBL484162

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12470982	0.89	PRMT5 (0.70)	CHEK2PRMT5NPC1RAB9ASMN1; SMN2
	SCHEMBL12471460	0.88	DHODH (0.59)	CHEK2NPC1RAB9ASMN1; SMN2GAA
	SCHEMBL484108	0.82	ACHE (0.57)	NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
	SCHEMBL28117058	0.82	NPC1 (0.69)	NPC1RAB9ASMN1; SMN2GAATP53
	SCHEMBL5579690	0.81	CHEK2 (0.59)	CHEK2PRMT5NPC1RAB9ASMN1; SMN2
	SCHEMBL6520239	0.79	PDE4A (0.67)	PRMT5NPC1RAB9ASMN1; SMN2GAA
	SCHEMBL784354	0.79	NPC1 (0.65)	CHEK2NPC1RAB9ASMN1; SMN2GAA
	SCHEMBL30693675	0.79	NPC1 (0.65)	CHEK2NPC1RAB9ASMN1; SMN2GAA
	SCHEMBL10745905	0.78	AMY1A (0.53)	CHEK2NPC1RAB9ASMN1; SMN2GAA
	SCHEMBL17973888	0.78	CHEK2 (0.67)	CHEK2PRMT5RAB9ATP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.