SCHEMBL484174

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL60856	0.98	AURKA (0.66)	AURKANPC1RAB9AGAAKDM4E
	SCHEMBL484484	0.88	NPC1 (0.61)	AURKANPC1RAB9AGAAKDM4E
	SCHEMBL24295036	0.86	NPC1 (0.84)	NPC1RAB9AGAAKDM4EMAPT
	SCHEMBL13085648	0.86	NPC1 (0.67)	AURKANPC1RAB9AGAAKDM4E
	SCHEMBL2178266	0.84	NPC1 (0.88)	NPC1RAB9AGAAKDM4EMAPT
	SCHEMBL29386825	0.84	NPC1 (0.88)	NPC1RAB9AGAAKDM4EMAPT
	SCHEMBL19675116	0.83	RAB9A (0.58)	NPC1RAB9AGAAKDM4EMAPT
	SCHEMBL2252555	0.83	NPC1 (0.92)	NPC1RAB9AGAAKDM4EMAPT
	SCHEMBL62491	0.83	RAB9A (0.62)	NPC1RAB9AGAAKDM4EMAPT
	SCHEMBL13836671	0.82	TCF4 (0.64)	AURKANPC1RAB9AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.