SCHEMBL4841932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4908782	0.83	AKR1C3 (0.45)	ALDH1A1TSHRAKR1C3MAPTKDM4E
	SCHEMBL10629619	0.82	ALDH1A1 (0.56)	ALDH1A1TSHRAKR1C3MAPTKDM4E
	SCHEMBL26332147	0.82	ALDH1A1 (0.56)	ALDH1A1TSHRAKR1C3MAPTKDM4E
	SCHEMBL9658870	0.74	AKR1C3 (0.53)	ALDH1A1AKR1C3MAPTKDM4EGAA
	SCHEMBL10981268	0.72	ALDH1A1 (0.58)	ALDH1A1TSHRMAPTKDM4EGAA
	SCHEMBL10981269	0.72	ALDH1A1 (0.58)	ALDH1A1TSHRMAPTKDM4EGAA
	SCHEMBL15442885	0.72	AKR1C3 (0.50)	ALDH1A1AKR1C3MAPTKDM4EGAA
	SCHEMBL26332150	0.72	AKR1C3 (0.50)	ALDH1A1AKR1C3MAPTKDM4EGAA
	SCHEMBL222105	0.69	ALDH1A1 (0.64)	ALDH1A1TSHRMAPTKDM4EGAA
	SCHEMBL2462984	0.69	AKR1C3 (0.82)	ALDH1A1AKR1C3KDM4EGLAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.