Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL484224 | 1.00 | HSD17B10 (0.34) | HSD17B10NPC1SLC6A9LMNAMAPT | |
| SCHEMBL483474 | 0.81 | GRIN1 (0.34) | GRIN1GRIN2AGRIN2BOPRM1OPRD1 | |
| SCHEMBL483691 | 0.76 | GRIN1 (0.35) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL2452095 | 0.68 | SIGMAR1 (0.33) | HSD17B10NPC1MEN1KMT2AOPRM1 | |
| SCHEMBL484166 | 0.68 | MAOB (0.40) | NPC1 | |
| SCHEMBL23611552 | 0.62 | GAA (0.33) | LMNAOPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL2834429 | 0.59 | ESR2 (0.35) | HSD17B10LMNAMAPTOPRM1OPRL1 | |
| SCHEMBL2837258 | 0.59 | KIF11 (0.37) | HSD17B10OPRM1OPRD1OPRK1 | |
| SCHEMBL1762490 | 0.58 | CRBN (0.43) | HSD17B10SLC6A9NPSR1GRIN1GRIN2A | |
| SCHEMBL25311909 | 0.57 | OPRL1 (0.42) | HSD17B10SLC6A9LMNAKMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934176-B1 | QUATERNARY ALPHA-AMINOCARBOXAMIDE DERIVATIVES AS MODULATORS OF VOLTAGE-GATED SODIUM CHANNELS | GLAXO GROUP LTD (GB) | 2012-02-01 | — | — | EP | disclosed |