Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226221 | 0.73 | OPRM1 (0.35) | NPC1OPRM1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL15094673 | 0.72 | APP (0.39) | SIGMAR1HTR2AHTR2CHTR2BHSD17B10 | |
| SCHEMBL20362064 | 0.71 | SLC6A2 (0.37) | NPC1POLBUSP2PDK2SLC6A2 | |
| SCHEMBL3312128 | 0.68 | NPSR1 (0.35) | HSD11B1ALDH1A1TSHR | |
| SCHEMBL3313722 | 0.68 | NPSR1 (0.35) | HSD11B1ALDH1A1TSHR | |
| SCHEMBL15266847 | 0.68 | RXFP1 (0.40) | SIGMAR1HTR2AHTR2CHTR2BHSD17B10 | |
| SCHEMBL15094568 | 0.68 | HCAR2 (0.39) | SIGMAR1HTR2AHTR2CHTR2BHSD17B10 | |
| SCHEMBL3312135 | 0.68 | NPSR1 (0.35) | HSD11B1ALDH1A1TSHR | |
| SCHEMBL484224 | 0.68 | HSD17B10 (0.34) | HSD17B10NPC1KMT2AMEN1OPRM1 | |
| SCHEMBL484225 | 0.68 | HSD17B10 (0.34) | HSD17B10NPC1KMT2AMEN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011112858-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-09-15 | — | — | WO | disclosed |