Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 8/20 | 0.47 |
| ▸ | MMP3 | P08254 | 5/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837872 | 0.90 | MMP8 (0.45) | MMP8MMP3MCL1LMNAPTGER3 | |
| SCHEMBL4834057 | 0.90 | MMP8 (0.45) | MMP8MMP3MCL1LMNAPTGER3 | |
| Hydrochloric Acid SCHEMBL4841948 | 0.89 | MMP8 (0.45) | MMP8MMP3MCL1LMNAPTGER3 | |
| SCHEMBL4837661 | 0.88 | MAPT (0.44) | MMP8MMP3MCL1LMNAPOLB | |
| SCHEMBL4845158 | 0.88 | MMP8 (0.58) | MMP8MMP3MCL1LMNAPOLB | |
| SCHEMBL4843626 | 0.86 | MCL1 (0.43) | MMP8MMP3MCL1LMNAPTGER3 | |
| SCHEMBL4843213 | 0.85 | MAPT (0.42) | MMP8MMP3LMNAPTGS2MAPT | |
| Hydrochloric Acid SCHEMBL4845617 | 0.84 | MAPT (0.41) | MMP8MMP3LMNAPTGS2MAPT | |
| SCHEMBL13986553 | 0.83 | MCL1 (0.62) | MMP8MMP3MCL1LMNAPOLB | |
| SCHEMBL4837892 | 0.82 | GHSR (0.41) | LMNAPTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | MMP8 3968/4885MMP3 3739/4885MCL1 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.