Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14084793 | 0.73 | ADORA2B (0.46) | ADORA2BADORA2ALMNAMAPTPDE4A | |
| SCHEMBL23974558 | 0.67 | ADORA2B (0.43) | ADORA2BADORA2AGDAPIK3CDPOLB | |
| SCHEMBL23974557 | 0.67 | CYP3A4 (0.37) | ADORA2BADORA2AGDAPIK3CDPOLB | |
| SCHEMBL24248823 | 0.64 | GDA (0.32) | ADORA2BADORA2AGDAPIK3CDPOLB | |
| SCHEMBL14580329 | 0.63 | — | — | |
| SCHEMBL23679320 | 0.63 | GABRA5 (0.36) | ADORA2BADORA2AGDAPIK3CDPOLB | |
| Caffeine SCHEMBL901194 | 0.63 | ADORA2B (1.00) | ADORA2BADORA2AGDAPIK3CDPOLB | |
| Isocaffiene SCHEMBL515995 | 0.63 | LMNA (0.57) | ADORA2BADORA2AGDAPIK3CDPOLB | |
| SCHEMBL23679322 | 0.63 | CCNE1 (0.40) | ADORA2BADORA2AGDAPIK3CDPOLB | |
| Caffeine SCHEMBL5671 | 0.63 | ADORA2B (1.00) | ADORA2BADORA2AGDAPIK3CDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9587061-B2 | Co-crosslinker systems for encapsulation films comprising urea compounds | EVONIK DEGUSSA GMBH (DE) | 2017-03-07 | — | — | US | disclosed |
| US-20160177013-A1 | CO-CROSSLINKER SYSTEMS FOR ENCAPSULATION FILMS COMPRISING UREA COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2016-06-23 | — | — | US | disclosed |
| US-7329658-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER INC (US) | 2008-02-12 | — | — | US | disclosed |
| CN-1768061-A | Pyrazolo[1,5-a][1,3,5]triazine derivatives as cannabinoid receptor ligands | PFIZER PROD INC (US) | 2006-05-03 | — | — | CN | disclosed |
| US-20040157839-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC | 2004-08-12 | — | — | US | disclosed |
| WO-2004014384-A2 | CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |
| US-4174445-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | disclosed |
| US-4048315-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157839-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | ADORA2B 469/4885ADORA2A 364/4885GDA 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.