Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 7/20 | 0.33 |
| ▸ | MMP3 | P08254 | 4/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836570 | 0.93 | SCN9A (0.34) | SCN9APTGER3MMP8MMP3RORC | |
| SCHEMBL4833568 | 0.89 | PPARD (0.42) | PPARDMMP8MMP3RORC | |
| SCHEMBL926678 | 0.86 | RORC (0.37) | PPARDPTGER3MMP8MMP3RORC | |
| SCHEMBL4841347 | 0.85 | SLC13A5 (0.41) | SCN9AMMP8MMP3PSEN1PSEN2 | |
| SCHEMBL4839015 | 0.84 | PSEN1 (0.39) | SCN9APTGER3MMP8MMP3PSEN1 | |
| SCHEMBL4832648 | 0.83 | SCN9A (0.48) | SCN9APTGER3MMP8MMP3TRPA1 | |
| SCHEMBL4845199 | 0.82 | FFAR4 (0.44) | SCN9APTGER3MMP8MMP3MMP1 | |
| SCHEMBL4841619 | 0.82 | ALDH1A1 (0.37) | PPARDMMP8MMP3RORCTRPA1 | |
| SCHEMBL4842900 | 0.80 | FFAR4 (0.43) | SCN9APTGER3MMP8MMP3MMP1 | |
| SCHEMBL4841693 | 0.80 | FFAR4 (0.43) | SCN9APTGER3MMP8MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | PPARD 258/4885SCN9A 1845/4885PTGER3 3044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.