Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837563 | 0.98 | RORC (0.44) | RORCFAAHADAMTS4MMP13ADAMTS5 | |
| SCHEMBL4842189 | 0.96 | RORC (0.43) | RORCADAMTS4MMP13ADAMTS5MMP1 | |
| SCHEMBL4841550 | 0.94 | RORC (0.44) | RORCTRPA1 | |
| SCHEMBL4843069 | 0.93 | RORC (0.43) | RORCADAMTS4MMP13ADAMTS5FFAR1 | |
| SCHEMBL4843218 | 0.93 | FAAH (0.41) | RORCFAAHADAMTS4MMP13ADAMTS5 | |
| SCHEMBL4841332 | 0.92 | RORC (0.43) | RORCTRPA1 | |
| SCHEMBL4833865 | 0.91 | RORC (0.42) | RORCFFAR1TRPA1BACE1 | |
| SCHEMBL4840183 | 0.91 | FAAH (0.40) | RORCFAAHADAMTS4MMP13ADAMTS5 | |
| SCHEMBL4842754 | 0.90 | RORC (0.44) | RORCTRPA1 | |
| SCHEMBL4843350 | 0.90 | RORC (0.43) | RORCFFAR1FFAR4TRPA1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | RORC 1777/4885FAAH 2327/4885ADAMTS4 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.