Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | CCR3 | P51677 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845655 | 1.00 | MCHR1 (0.66) | MCHR1SIGMAR1CCR3 | |
| SCHEMBL4117894 | 0.94 | MCHR1 (0.65) | MCHR1SIGMAR1 | |
| SCHEMBL10135593 | 0.87 | MCHR1 (0.51) | MCHR1CCR3 | |
| SCHEMBL10135613 | 0.87 | MCHR1 (0.51) | MCHR1CCR3 | |
| SCHEMBL178929 | 0.87 | KMT2A (0.63) | MCHR1SIGMAR1 | |
| SCHEMBL2241424 | 0.87 | KMT2A (0.63) | MCHR1SIGMAR1 | |
| SCHEMBL2241423 | 0.87 | KMT2A (0.63) | MCHR1SIGMAR1 | |
| SCHEMBL17269909 | 0.85 | DRD2 (0.64) | MCHR1 | |
| SCHEMBL29725665 | 0.84 | DRD4 (0.60) | MCHR1SIGMAR1 | |
| SCHEMBL23753469 | 0.84 | SIGMAR1 (0.54) | MCHR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423030-B2 | 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof | SANOFI-AVENTIS (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20070099895-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-05-03 | — | — | US | disclosed |
| EP-1737840-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005103033-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2005-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099895-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | CYP11B2, CYP11B1, GOT2 | MCHR1 1335/4885SIGMAR1 1593/4885CCR3 4648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.