SCHEMBL4843481

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4843493	0.94	PARP1 (0.37)	PARP1NR1H2FAAHUSP2SMN1; SMN2
	SCHEMBL31377274	0.92	PARP1 (0.41)	PARP1NR1H2MEN1ALDH1A1MAPT
	SCHEMBL4836552	0.85	NR1H2 (0.43)	PARP1NR1H2MEN1ALDH1A1MAPT
	SCHEMBL4844477	0.85	ALDH1A1 (0.39)	PARP1NR1H2MEN1ALDH1A1MAPT
	SCHEMBL4840168	0.83	NR1H2 (0.46)	PARP1NR1H2MEN1ALDH1A1MAPT
	SCHEMBL5790219	0.83	NR1H2 (0.46)	PARP1NR1H2MEN1ALDH1A1MAPT
	SCHEMBL21193443	0.83	NR1H2 (0.42)	PARP1NR1H2MEN1ALDH1A1MAPT
	SCHEMBL18286688	0.83	NR1H2 (0.42)	PARP1NR1H2MEN1ALDH1A1MAPT
	SCHEMBL4836992	0.83	GPR119 (0.39)	PARP1NR1H2MEN1ALDH1A1MAPT
	SCHEMBL6729203	0.82	NR1H2 (0.41)	PARP1NR1H2MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.