Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL9631269 | 0.98 | CYP3A4 (0.55) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL29024165 | 0.83 | CYP3A4 (0.60) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL21057058 | 0.83 | CYP3A4 (0.60) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Ethyl Chloride SCHEMBL2149959 | 0.82 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Methoxymethane SCHEMBL9622762 | 0.82 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Methylene Chloride SCHEMBL958149 | 0.82 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL1654463 | 0.81 | TDP1 (0.57) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL6260735 | 0.80 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Methoxymethane SCHEMBL15347765 | 0.79 | CYP3A4 (0.71) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Methoxymethane SCHEMBL28458551 | 0.79 | CYP3A4 (0.71) | CYP3A4TDP1ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1011 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713317-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | Adama Agan Ltd. (IL) | 2026-03-25 | — | — | EP | claimed |
| WO-2024236570-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | ADAMA AGAN LTD. (IL) | 2024-11-21 | — | — | WO | claimed |
| CN-118878430-A | Compound, synthesis method thereof and synthesis method of 5, 6-dihydroxyindole | 谱尼生物医药科技(上海)有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118638086-A | Full synthesis method of tetrahydronaphtho cyclic ether lignan STELLERALIGNAN | 西南交通大学 | 2024-09-13 | — | — | CN | claimed |
| CN-118439921-A | Preparation method of trans-1-bromo-4- [4- (trifluoroalkyl) cyclohexyl ] benzene compound | 陕西莱特光电材料股份有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-118317946-A | Processes and intermediates for the preparation of baratinib | 因赛特公司 | 2024-07-09 | — | — | CN | claimed |
| CN-117603169-A | Method for synthesizing key intermediate of pilocarpine | 杭州澳赛诺生物科技有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117043152-A | Methods and intermediates for preparing JAK1 inhibitors | 因赛特公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116903625-A | EGFR inhibitor intermediate and synthetic method and application thereof | 广州安岩仁医药科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116761792-A | Methods and intermediates for preparing JAK inhibitors | 因赛特公司 | 2023-09-15 | — | — | CN | claimed |
| CN-107759601-B | Preparation method of JAK inhibitor and salt thereof | 苏州旺山旺水生物医药有限公司 | 2020-09-11 | — | — | CN | claimed |
| CN-104844546-A | Method for synthesizing salvianolic acid B and related derivatives | XIE YANG | 2015-08-19 | — | — | CN | claimed |
| CN-103937522-B | Separation method for phenol compounds and nitrogen-containing compounds in coal tar | WUHUAN ENGINEERING CO LTD | 2015-07-01 | — | — | CN | claimed |
| US-7217729-B2 | Substituted indoles, process for the production thereof and use thereof for combatting pain | GRUNENTHAL GMBH (DE) | 2007-05-15 | — | — | US | claimed |
| US-7041662-B2 | Substituted benzo [b] azepin-2-one compounds | GRUNENTHAL GMBH (DE) | 2006-05-09 | — | — | US | claimed |
| EP-1472221-B1 | SUBSTITUTED INDOLES, METHOD FOR PRODUCTION AND USE THEREOF FOR THE INHIBITION OF PAIN | GRUENENTHAL GMBH (DE) | 2006-03-22 | — | — | EP | claimed |
| EP-1444206-B1 | SUBSTITUTED BENZO[B]AZEPIN-2-ONE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2006-03-15 | — | — | EP | claimed |
| US-20040224980-A1 | Substituted 1H-quinolin-2-one compounds | GRUNENTHAL GMBH (DE) | 2004-11-11 | — | — | US | claimed |
| US-20040224954-A1 | Substituted 1H-quinoxalin-2-one compounds and substituted 4-aryl- and 4-heteroarylcyclohexane compounds | GRUNENTHAL GMBH (DE) | 2004-11-11 | — | — | US | claimed |
| US-20040225003-A1 | 4,6-Dimethyl-3-{[3'-(N,N-dimethylaminomethyl)-4-hydroxy-4'-(3''-methoxyphenyl)-cyclohexylamino]-methyl}-1H-indole 2-carboxylic acid ethyl ester or other derivatives of substituted indoles; for treatment or prevention of neurodegenerative diseases, psychological disorders, AIDS, inflammation or allergies | GRUNENTHAL GMBH (DE) | 2004-11-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040225003-A1 | 4,6-Dimethyl-3-{[3'-(N,N-dimethylaminomethyl)-4-hydroxy-4'-(3''-methoxyphenyl)-cyclohexylamino]-methyl}-1H-indole 2-carboxylic acid ethyl ester or other derivatives of substituted indoles; for treatment or prevention of neurodegenerative diseases, psychological disorders, AIDS, inflammation or allergies | HNMT, HTR6, HTR3C | CYP3A4 399/4885TDP1 731/4885ESR1 1386/4885 |
| US-20040224954-A1 | Substituted 1H-quinoxalin-2-one compounds and substituted 4-aryl- and 4-heteroarylcyclohexane compounds | NQO2, NQO1, CYP2C8 | CYP3A4 23/4885TDP1 2741/4885ESR1 4496/4885 |
| US-20040224980-A1 | Substituted 1H-quinolin-2-one compounds | NQO1, QARS1, QDPR | CYP3A4 159/4885TDP1 2687/4885ESR1 3774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.