SCHEMBL4843667

SCHEMBL4843667

CC(C)CC1CCCC(O)C1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.32
ANPEP P15144 1/20 0.32
CNR2 P34972 2/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17834055 1.00 LMNA (0.33) LMNACYP2C9TSHRANPEPCNR2
SCHEMBL24448809 1.00 LMNA (0.33) LMNACYP2C9TSHRANPEPCNR2
SCHEMBL21038564 1.00 LMNA (0.33) LMNACYP2C9TSHRANPEPCNR2
SCHEMBL17834053 1.00 LMNA (0.33) LMNACYP2C9TSHRANPEPCNR2
SCHEMBL4835227 0.96 TSHR (0.38) LMNACYP2C9TSHRDPP4
SCHEMBL4845201 0.94 TSHR (0.36) LMNACYP2C9TSHR
SCHEMBL4844966 0.86 TSHR (0.41) TSHR
SCHEMBL102291 0.86 LMNA (0.36) LMNACYP2C9
SCHEMBL14652016 0.86 LMNA (0.36) LMNACYP2C9
SCHEMBL10974716 0.84 ANPEP (0.32) ANPEPDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62030191-A None JP disclosed
US-20220204539-A1 CD73 INHIBITORS BIOARDIS LLC 2022-06-30 US disclosed
WO-2020210938-A1 QUINAZOLINE DERIVATIVES AS CD73 INHIBITORS BIOARDIS LLC (US) 2020-10-22 WO disclosed
US-10633361-B2 Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex INTREXON CORPORATION (US) 2020-04-28 US disclosed
CN-108271909-A Oral delivery product including three-dimension object 加优有限责任公司 2018-07-13 CN disclosed
US-20180161329-A1 PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF TEIJIN PHARMA LIMITED (JP) 2018-06-14 US disclosed
EP-3305785-A1 PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Teijin Pharma Limited (JP) 2018-04-11 EP disclosed
US-20170204079-A1 Chiral Diacylhydrazine Ligands for Modulating the Expression of Exogenous Genes via an Ecdysone Receptor Complex INTREXON CORPORATION (US) 2017-07-20 US disclosed
WO-2016194831-A1 PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF 帝人ファーマ株式会社 2016-12-08 WO disclosed
US-20160168090-A1 NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES MERCK PATENT GMBH (DE) 2016-06-16 US disclosed
US-20030155836-A1 SMALL-SIZE MOTOR UDA SHIGENORI (JP) 2003-08-21 US disclosed
EP-0977720-B1 PERFUMES COMPRISING 3-ALKYLCYCLOALKANOLS QUEST INT (NL) 2002-06-19 EP disclosed
US-6313087-B1 PERFUME COMPOSITION COMPRISING MIXTURE OF FRAGRANCE MATERIALS, INCLUDING AT LEAST ONE 3-ALKYLCYCLOALKANOL, PROVIDING MUGUET-TYPE ODOR NOTE TO SAID COMPOSITION QUEST INTERNATIONAL BV (NL) 2001-11-06 US disclosed
WO-2000036933-A1 USE OF N-NEOHEXYL-α-ASPARTYL-L-PHENYLALANINE METHYL ESTER AS A FLAVOR MODIFIER THE NUTRASWEET COMPANY (US) 2000-06-29 WO disclosed
EP-0977720-A1 PERFUMES COMPRISING 3-ALKYLCYCLOALKANOLS QUEST INTERNATIONAL B.V. (NL) 2000-02-09 EP disclosed
WO-1998047842-A1 PERFUMES COMPRISING 3-ALKYLCYCLOALKANOLS QUEST INTERNATIONAL B.V. (NL) 1998-10-29 WO disclosed
EP-0209617-B1 SMALL-SIZE MOTOR MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-01-29 EP disclosed
JP-S6230191-A LUBRICANT MATSUSHITA ELECTRIC IND CO LTD 1987-02-09 JP disclosed
EP-0209617-A1 Small-size motor MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-01-28 EP disclosed
JP-S06230191-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168090-A1 NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES P2RX3, P2RX7, P2RX2 LMNA 2777/4885CYP2C9 2542/4885TSHR 2658/4885
US-20180161329-A1 PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF CDK4, CDK6, CDK16 LMNA 3947/4885CYP2C9 743/4885TSHR 2977/4885
US-20170204079-A1 Chiral Diacylhydrazine Ligands for Modulating the Expression of Exogenous Genes via an Ecdysone Receptor Complex NR2E3, CRYZ, TCF12 LMNA 4803/4885CYP2C9 4174/4885TSHR 720/4885
US-10633361-B2 Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex NR2E3, CRYZ, TCF12 LMNA 4803/4885CYP2C9 4174/4885TSHR 720/4885
US-20220204539-A1 CD73 INHIBITORS ENTPD5, ENTPD1, ENTPD2 LMNA 2760/4885CYP2C9 3800/4885TSHR 1674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.