Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854156 | 0.84 | HSD17B10 (0.40) | ALOX15ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL4847774 | 0.81 | ALOX15 (0.43) | ALOX15ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL1456970 | 0.77 | CYP3A4 (0.55) | ALOX15ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL572491 | 0.77 | EP300 (0.42) | ALOX15ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL30968537 | 0.75 | CYP3A4 (0.40) | ALOX15ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL29782293 | 0.75 | CYP3A4 (0.59) | ALOX15ALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL911858 | 0.75 | CYP3A4 (0.59) | ALOX15ALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL14908341 | 0.75 | EP300 (0.41) | ALOX15ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL16555577 | 0.75 | CYP3A4 (0.40) | ALOX15ALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29972242 | 0.75 | CYP3A4 (0.52) | ALOX15ALDH1A1HSD17B10MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115754028-A | Method for separating and detecting aniline impurities in fluvastatin | 重庆医药工业研究院有限责任公司 | 2023-03-07 | — | — | CN | claimed |
| CN-114621106-A | Preparation method of tyrosine kinase drug intermediate | 重庆医药工业研究院有限责任公司 | 2022-06-14 | — | — | CN | claimed |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2005-06-30 | — | — | US | claimed |
| CN-1616412-A | Process for the preparation of halogen containing 4-amino phenols | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | claimed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | claimed |
| CN-115754028-A | Method for separating and detecting aniline impurities in fluvastatin | 重庆医药工业研究院有限责任公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115754028-A | Method for separating and detecting aniline impurities in fluvastatin | 重庆医药工业研究院有限责任公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-114149449-B | Alkynyl-coupled difluorophenyl pyridone HIV integrase inhibitor, preparation method and application | 吉斯凯(苏州)制药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| EP-3689351-B1 | QUINOLINE DERIVATIVE AND APPLICATION THEREOF AS TYROSINE KINASE INHIBITOR | CHONGQING PHARMACEUTICAL INDUSTRIAL RES INSTITUTE CO LTD (CN) | 2022-11-02 | — | — | EP | disclosed |
| CN-114621106-A | Preparation method of tyrosine kinase drug intermediate | 重庆医药工业研究院有限责任公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621106-A | Preparation method of tyrosine kinase drug intermediate | 重庆医药工业研究院有限责任公司 | 2022-06-14 | — | — | CN | disclosed |
| US-20220175756-A1 | APPLICATION OF COMBINATION OF QUINOLINE DERIVATIVE AND IMMUNOMODULATOR IN PREPARATION OF ANTITUMOR DRUGS | CHONGQING PHARMACEUTICAL INDUSTRIAL RESEARCH INSTITUTE CO., LTD. (CN) | 2022-06-09 | — | — | US | disclosed |
| US-20200262791-A1 | QUINOLINE DERIVATIVE AND USE THEREOF AS TYROSINE KINASE INHIBITOR | Chongqing Pharmaceutical Industrial Research Institute Co. Ltd. (CN) | 2020-08-20 | — | — | US | disclosed |
| EP-3689351-A1 | QUINOLINE DERIVATIVE AND APPLICATION THEREOF AS TYROSINE KINASE INHIBITOR | Medshine Discovery Inc. (CN) | 2020-08-05 | — | — | EP | disclosed |
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |
| US-20080139795-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| US-7358397-B2 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2005-06-30 | — | — | US | disclosed |
| CN-1616412-A | Process for the preparation of halogen containing 4-amino phenols | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | disclosed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139795-A1 | Preparation of halogenated 4-aminophenols | CYP4X1, CYP4B1, PAH | ALOX15 3542/4885ALDH1A1 569/4885HSD17B10 440/4885 |
| US-20200262791-A1 | QUINOLINE DERIVATIVE AND USE THEREOF AS TYROSINE KINASE INHIBITOR | ABL1, JAK2, FLT3 | ALOX15 4647/4885ALDH1A1 2450/4885HSD17B10 2595/4885 |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | CYP4X1, HPD, CYP4F8 | ALOX15 3692/4885ALDH1A1 956/4885HSD17B10 541/4885 |
| US-20220175756-A1 | APPLICATION OF COMBINATION OF QUINOLINE DERIVATIVE AND IMMUNOMODULATOR IN PREPARATION OF ANTITUMOR DRUGS | IFNG, IL2, MCL1 | ALOX15 3761/4885ALDH1A1 1376/4885HSD17B10 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.