SCHEMBL484445

SCHEMBL484445

Cc1cccc(Cl)c1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 2/20 0.55
FABP4 P15090 2/20 0.55
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TYK2 P29597 1/20 0.51
TRPM4 Q8TD43 1/20 0.49
DPP4 P27487 1/20 0.48
KMT2A Q03164 1/20 0.47
PBRM1 Q86U86 1/20 0.47
KDM4E B2RXH2 2/20 0.47
HSD17B10 Q99714 2/20 0.47
TSHR P16473 1/20 0.47
NOTUM Q6P988 1/20 0.46
FEN1 P39748 1/20 0.46
HPGD P15428 1/20 0.45
RORC P51449 2/20 0.45
CYP2C9 P11712 1/20 0.45
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30676249 1.00 FABP3 (0.55) FABP3FABP4ALDH1A1TDP1L3MBTL1
SCHEMBL1514599 0.90 FABP3 (0.51) FABP3FABP4ALDH1A1TDP1L3MBTL1
SCHEMBL19359128 0.86 ALDH1A1 (0.47) FABP3FABP4ALDH1A1TDP1L3MBTL1
SCHEMBL80183 0.84 ALDH1A1 (0.64) FABP3FABP4ALDH1A1DPP4KMT2A
SCHEMBL355272 0.84 TDP1 (0.61) FABP3FABP4ALDH1A1TDP1L3MBTL1
SCHEMBL13100052 0.83 ALDH1A1 (0.52) FABP3FABP4ALDH1A1TYK2TRPM4
SCHEMBL476833 0.83 ALDH1A1 (0.71) FABP3FABP4ALDH1A1TDP1L3MBTL1
SCHEMBL11466346 0.81 TDP1 (0.59) FABP3FABP4ALDH1A1TDP1L3MBTL1
SCHEMBL6907913 0.81 TDP1 (0.59) FABP3FABP4ALDH1A1TDP1L3MBTL1
SCHEMBL6916441 0.81 TDP1 (0.59) FABP3FABP4ALDH1A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 676 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113683499-B Method for preparing Du Weili siberian intermediate 上海皓鸿生物医药科技有限公司 2024-01-30 CN claimed
CN-113683499-A Method for preparing Duvirucisib intermediate 上海皓鸿生物医药科技有限公司 2021-11-23 CN claimed
CN-106588604-A Method for preparing chlorobenzaldehyde through continuous oxidization of m-chlorobenzene 常州大学 2017-04-26 CN claimed
JP-4643102-B2 2011-03-02 JP claimed
EP-1240130-B1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES SABIC INNOVATIVE PLASTICS IP (NL) 2009-05-06 EP claimed
EP-1235782-B1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GEN ELECTRIC (US) 2004-02-18 EP claimed
US-6469205-B1 PRODUCING 4-CHLOROPHTHALIC ANHYDRIDE BY OXIDIZING A SUBSTRATE COMPRISING 4-CHLORO-ORTHO-XYLENE GENERAL ELECTRIC COMPANY 2002-10-22 US claimed
US-6465685-B1 SUCH AS CHLORO-O-XYLENE, ARE OXIDIZED IN A SOLVENT IN THE PRESENCE OF A METAL COMPOUND CATALYST WITH ADDITION OF PROMOTER AFTER THE REACTION HAS PROCEEDED TO AN INTERMEDIATE STAGE; PRODUCT COMPRISES CHLOROPHTHALIC ACID OR ANHYDRIDE GENERAL ELECTRIC COMPANY 2002-10-15 US claimed
EP-1240130-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2002-09-18 EP claimed
EP-1235781-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2002-09-04 EP claimed
EP-1235782-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2002-09-04 EP claimed
US-6399790-B1 USING METAL CATALYST GENERAL ELECTRIC COMPANY 2002-06-04 US claimed
WO-2001038282-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2001-05-31 WO claimed
WO-2001038281-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2001-05-31 WO claimed
WO-2001038280-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2001-05-31 WO claimed
US-12447151-B2 Alkyne derivative, preparation method for same, and uses thereof HIS PHARMACEUTICAL CO., LTD. (CN) 2025-10-21 US disclosed
US-12378254-B2 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators JANSSEN PHARMACEUTICA NV (BE) 2025-08-05 US disclosed
US-4252659-A Process for the production of overbased manganese salts of organic acids TENNECO CHEMICALS, INC. (US) 1981-02-24 US disclosed
US-4179385-A CARBON DIOXIDE, SOLVENT SYSTEM CONTAINING WATER TENNECO CHEMICALS, INC. (US) 1979-12-18 US disclosed
US-RE28972-E SEDATIVES, ANTICONVULSANTS BOEHRINGER INGELHEIM GMBH (DT) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378254-B2 Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators HCRTR2, HCRTR1, OXTR FABP3 3575/4885FABP4 3536/4885ALDH1A1 3132/4885
US-12447151-B2 Alkyne derivative, preparation method for same, and uses thereof PIK3CD, PIK3R5, PIK3CA FABP3 2306/4885FABP4 3406/4885ALDH1A1 1231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.