SCHEMBL4844564

SCHEMBL4844564

C[Si](Cl)(Cl)CCc1cccc(CCl)c1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TAAR1 Q96RJ0 4/20 0.34
NOS1 P29475 2/20 0.34
NOS2 P35228 2/20 0.34
AOC3 Q16853 1/20 0.33
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
CYP2D6 P10635 1/20 0.32
NOS3 P29474 1/20 0.32
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4850067 0.89 TSHR (0.38) TSHRMEN1KMT2ATAAR1NOS1
SCHEMBL4839367 0.84 TSHR (0.40) TSHRMEN1KMT2ATAAR1NOS1
SCHEMBL4848522 0.79 CA2 (0.34) TAAR1
SCHEMBL8418694 0.79 TSHR (0.34) TSHRMEN1KMT2ATAAR1NOS1
SCHEMBL9311601 0.79 TSHR (0.48) TSHRMEN1KMT2ATAAR1NOS1
SCHEMBL926607 0.78 TSHR (0.40) TSHRTAAR1AOC3MTNR1AMTNR1B
SCHEMBL523393 0.77 TDP1 (0.48) TSHRTAAR1AOC3CYP2D6
SCHEMBL225197 0.76 TSHR (0.54) TSHRMEN1KMT2ATAAR1NOS1
SCHEMBL13064226 0.75 TSHR (0.42) TSHRMEN1KMT2ATAAR1LPL
SCHEMBL28065354 0.75 TDP1 (0.52) TSHRMEN1KMT2ATAAR1NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7463400-B1 Electrochromic display device FUJI XEROX CO., LTD. (JP) 2008-12-09 US disclosed
US-6284365-B1 FOR CONTROLLING PHYSICAL PROPERTIES OF SURFACE AND INTERFACE OF SOLID ARTICLE SUCH AS WETTABILITY, ADHESIVE PROPERTY, SURFACE ENERGY, DISPERSABILITY, CHEMICAL RESISTANCE FUJI XEROX CO., LTD. (JP) 2001-09-04 US disclosed