Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9454763 | 0.93 | MAOA (0.56) | TSHRMEN1KMT2AMAOAMAOB | |
| SCHEMBL225197 | 0.91 | TSHR (0.54) | TSHRMEN1KMT2ATAAR1NOS1 | |
| SCHEMBL28326229 | 0.90 | TSHR (0.45) | TSHRMEN1KMT2AMAOAMAOB | |
| SCHEMBL33722031 | 0.90 | TSHR (0.45) | TSHRMEN1KMT2AMAOAMAOB | |
| SCHEMBL13064226 | 0.85 | TSHR (0.42) | TSHRMEN1KMT2ATAAR1DRD2 | |
| SCHEMBL28065354 | 0.85 | TDP1 (0.52) | TSHRMEN1KMT2ATAAR1NOS1 | |
| SCHEMBL27999917 | 0.85 | TDP1 (0.52) | TSHRMEN1KMT2AMAOAMAOB | |
| SCHEMBL13857069 | 0.83 | TSHR (0.48) | TSHRMEN1KMT2ATAAR1 | |
| SCHEMBL23794950 | 0.82 | LPL (0.49) | — | |
| SCHEMBL4839367 | 0.82 | TSHR (0.40) | TSHRMEN1KMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6080894-A | — | — | None | — | — | JP | disclosed |
| JP-H0680894-A | AZO-BASED COMPOUND | MITA IND CO LTD | 1994-03-22 | — | — | JP | disclosed |