Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.61 |
| ▸ | PI4KA | P42356 | 2/20 | 0.61 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.61 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.61 |
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.61 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.61 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.61 |
| ▸ | GAPDH | P04406 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | STAT6 | P42226 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.61 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546108 | 1.00 | ADORA2A (0.76) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| Phosphoric Acid SCHEMBL23748616 | 0.95 | ADORA2A (0.69) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL5549330 | 0.89 | ADORA2A (0.73) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL5936728 | 0.89 | ADORA2A (0.73) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL29601760 | 0.89 | ADORA2A (0.73) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL29502687 | 0.89 | ADORA2A (0.66) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL5416581 | 0.88 | ADORA2A (0.76) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL5417952 | 0.88 | ADORA2A (0.76) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL30367149 | 0.88 | ADORA2A (0.79) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL26130576 | 0.88 | ADORA2A (0.79) | ADORA2AADORA3PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8506926-B2 | Labeled purine nucleoside analog; imaging in vivo tumors, organs, tissues by positron emission tomography; administered intravenously, at more than one time point, by infusion over a period of five minutes or more; cancer, cardiac and neurological imaging studies | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-08-13 | — | — | US | disclosed |
| US-7381820-B2 | α-1-phosphorylated-2-deoxy-2-fluoroarabinoside and process for producing 2′-deoxy-2′-fluoro-β-d-arabinonucleoside | YAMASA CORPORATION (JP) | 2008-06-03 | — | — | US | disclosed |
| US-20080056988-A1 | [18F]-FURANOSYLPURINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-03-06 | — | — | US | disclosed |
| US-7273600-B2 | [18F]-furanosylpurine derivatives and uses thereof | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-09-25 | — | — | US | disclosed |
| US-20070135627-A1 | Alpha-1-phosphorylated-2-deoxy-2-fluoroarabinoside and process for producing 2'-deoxy-2'-fluoro-beta-d-arabinonucleoside | KOHEL YAMADA, ETAL | 2007-06-14 | — | — | US | disclosed |
| EP-1676853-A1 | ALPHA-1-PHOSPHORYLATED-2-DEOXY-2-FLUOROARABINOSIDE AND PROCESS FOR PRODUCING 2 -DEOXY-2 -FLUORO-BETA-D-ARABINONUCLEOSID E | YAMASA CORPORATION (JP) | 2006-07-05 | — | — | EP | disclosed |
| US-20040265232-A1 | [18F]-furanosylpurine derivatives and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-30 | — | — | US | disclosed |
| WO-2004096138-A2 | [18F]-FURANOSYLPURINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135627-A1 | Alpha-1-phosphorylated-2-deoxy-2-fluoroarabinoside and process for producing 2'-deoxy-2'-fluoro-beta-d-arabinonucleoside | TYMP, PNP, DUT | ADORA2A 314/4885ADORA3 363/4885PI4KA 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.