Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.62 |
| ▸ | PI4KA | P42356 | 2/20 | 0.62 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.62 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.62 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.62 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.62 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.62 |
| ▸ | GAPDH | P04406 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
| ▸ | STAT6 | P42226 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549330 | 1.00 | ADORA2A (0.73) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL5936728 | 1.00 | ADORA2A (0.73) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| Phosphoric Acid SCHEMBL21465094 | 0.94 | ADORA2A (0.67) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL14429174 | 0.92 | ADORA3 (0.68) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL4845625 | 0.89 | ADORA2A (0.76) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL546108 | 0.89 | ADORA2A (0.76) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL17117141 | 0.88 | ADORA2A (0.78) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL465644 | 0.88 | ADORA2A (0.78) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL13929067 | 0.88 | ADORA2A (0.78) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL19229274 | 0.88 | ADORA2A (0.71) | ADORA2AADORA3PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12582609-B2 | Cancer vaccines | MODERNATX, INC. (US) | 2026-03-24 | — | — | US | disclosed |
| EP-4709417-A2 | POLYNUCLEOTIDES ENCODING NOROVIRUS VP1 ANTIGENS AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4689071-A2 | MRNA THERAPEUTICS FOR OOCYTE MATURATION | Eastern Virginia Medical School (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-4608440-A1 | RNA MOLECULES ENCODING RSV-F AND VACCINES CONTAINING THEM | Pfizer Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| EP-4598946-A1 | NUCLEIC ACID MOLECULES ENCODING TRIF AND ADDITIONALPOLYPEPTIDES AND THEIR USE IN TREATING CANCER | Flagship Pioneering Innovations V, Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| US-12377136-B2 | Polynucleotides encoding porphobilinogen deaminase for the treatment of acute intermittent porphyria | MODERNATX, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| WO-2025126071-A1 | RNA MOLECULES | PFIZER INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| EP-4569112-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING AT ALTERNATIVE SPLICE SITES | Remix Therapeutics Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| US-20250135010-A1 | CONCATEMERIC PEPTIDE EPITOPE RNAS | MODERNATX, INC. (US) | 2025-05-01 | — | — | US | disclosed |
| US-20250122494-A1 | METHODS FOR SEPARATING MOLECULAR SPECIES OF GUANINE-RICH OLIGONUCLEOTIDES | AMGEN INC. (US) | 2025-04-17 | — | — | US | disclosed |
| CN-115837014-A | Polynucleotides encoding relaxin | 摩登纳特斯有限公司 | 2023-03-24 | — | — | CN | disclosed |
| WO-2023044346-A2 | VACCINES FOR CORONAVIRUS PREVENTION AND TREATMENT | AUSPER BIOPHARMA CO., LTD. (CN) | 2023-03-23 | — | — | WO | disclosed |
| WO-2023042099-A2 | VACCINES FOR CORONAVIRUS PREVENTION AND TREATMENT | AUSPER BIOPHARMA CO., LTD. (CN) | 2023-03-23 | — | — | WO | disclosed |
| WO-2023021421-A1 | LOW-DOSE LYOPHILIZED RNA VACCINES AND METHODS FOR PREPARING AND USING THE SAME | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023021427-A1 | FREEZE-DRYING OF LIPID NANOPARTICLES (LNPS) ENCAPSULATING RNA AND FORMULATIONS THEREOF | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2023-02-23 | — | — | WO | disclosed |
| US-20220325287-A1 | THANOTRANSMISSION POLYPEPTIDES AND THEIR USE IN TREATING CANCER | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2022-10-13 | — | — | US | disclosed |
| WO-2022212784-A1 | THANOTRANSMISSION POLYPEPTIDES AND THEIR USE IN TREATING CANCER | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2022-10-06 | — | — | WO | disclosed |
| WO-2022187698-A1 | VLP ENTEROVIRAL VACCINES | MODERNATX, INC. (US) | 2022-09-09 | — | — | WO | disclosed |
| CN-109640962-B | Polynucleotides encoding relaxin | 摩登纳特斯有限公司 | 2022-07-19 | — | — | CN | disclosed |
| US-20220152178-A1 | CONCATEMERIC PEPTIDE EPITOPE RNAS | MODERNATX, INC. (US) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12377136-B2 | Polynucleotides encoding porphobilinogen deaminase for the treatment of acute intermittent porphyria | HMBS, ALAD, LNPEP | ADORA2A 1215/4885ADORA3 1844/4885PI4KA 2080/4885 |
| US-12582609-B2 | Cancer vaccines | RNMT, MICA, NSUN2 | ADORA2A 4471/4885ADORA3 4110/4885PI4KA 2890/4885 |
| US-20220325287-A1 | THANOTRANSMISSION POLYPEPTIDES AND THEIR USE IN TREATING CANCER | AREG, STING1, TRDMT1 | ADORA2A 888/4885ADORA3 980/4885PI4KA 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.