SCHEMBL4846527

SCHEMBL4846527

Cl[Zr](Cl)([SiH2]C1CC1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7641474 0.78 HTR6 (0.33) HTR6HTR2A
SCHEMBL7638459 0.75 HTR6 (0.34) HTR6HTR2A
SCHEMBL7055500 0.74 HTR6 (0.33) HTR6HTR2A
SCHEMBL3820447 0.72 SIGMAR1 (0.35) HTR6HTR2A
SCHEMBL3380394 0.72 HTR2A (0.35) HTR6HTR2A
SCHEMBL7947949 0.72 HTR6 (0.39) HTR6HTR2A
SCHEMBL218232 0.72 HTR2A (0.35) HTR6HTR2A
SCHEMBL3304642 0.71
SCHEMBL30577433 0.70 HTR2A (0.40) HTR6HTR2A
SCHEMBL3385286 0.69 HTR6 (0.33) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6344577-B1 COMPLEXING METAL, SILICON HYDROCARBYL COMPOUNDS AND CYCLOPENTADIENE FINA TECHNOLOGY, INC. 2002-02-05 US claimed
US-6117957-A COORDINATION CATALYST FINA TECHNOLOGY, INC. (US) 2000-09-12 US claimed
US-5846896-A Metallocene catalyst systems FINA TECHNOLOGY, INC. (US) 1998-12-08 US claimed
EP-0336128-B2 Process for preparing an alpha-olefin polymer TARGOR GMBH (DE) 1998-11-18 EP claimed
EP-0284708-B1 Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. FINA TECHNOLOGY (US) 1996-01-31 EP claimed
US-12071502-B2 Method of making an ethylene-propylene copolymer KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-08-27 US disclosed
US-20240228677-A9 METHOD OF MAKING AN ETHYLENE-PROPYLENE COPOLYMER KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-07-11 US disclosed
US-20240132635-A1 METHOD OF MAKING AN ETHYLENE-PROPYLENE COPOLYMER KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-04-25 US disclosed
US-11926691-B2 Method for making and using a supported zinc aluminum layered double hydroxide catalyst KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-03-12 US disclosed
US-20240034818-A1 METHOD FOR MAKING AND USING A SUPPORTED ZINC ALUMINUM LAYERED DOUBLE HYDROXIDE CATALYST KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-02-01 US disclosed
US-11827734-B1 Method of making a polyolefin KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-11-28 US disclosed
US-11746164-B1 Method of making a polyolefin nanocomposite KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-09-05 US disclosed
US-6649712-B2 Changing the components and structure of the metallocene catalysts; melting point is controlled by the number of inversions in the xylene insoluble fraction of the polymer FINA TECHNOLOGY, INC. 2003-11-18 US disclosed
US-20020193537-A1 Method for varying the melting points and molecular weights of polyolefins using metallocene catalyst systems EWEN JOHN A (US) 2002-12-19 US disclosed
US-20020111444-A1 Alpha olefin polymer products and catalyst systems EWEN JOHN A (US) 2002-08-15 US disclosed
US-6344577-B1 COMPLEXING METAL, SILICON HYDROCARBYL COMPOUNDS AND CYCLOPENTADIENE FINA TECHNOLOGY, INC. 2002-02-05 US disclosed
US-6117957-A COORDINATION CATALYST FINA TECHNOLOGY, INC. (US) 2000-09-12 US disclosed
US-5846896-A Metallocene catalyst systems FINA TECHNOLOGY, INC. (US) 1998-12-08 US disclosed
EP-0284708-B1 Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. FINA TECHNOLOGY (US) 1996-01-31 EP disclosed
EP-0284708-A1 Metallocene catalyst systems for olefin polymerization having a silicon hydrocarbyl bridge. FINA TECHNOLOGY, INC. (US) 1988-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193537-A1 Method for varying the melting points and molecular weights of polyolefins using metallocene catalyst systems MRPS22, MRPS35, MCRS1 HTR6 2528/4885HTR2A 1388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.