Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226976 | 0.77 | L3MBTL1 (0.52) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9003269 | 0.77 | MAPT (0.70) | HTTMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4847201 | 0.76 | TAAR1 (0.53) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8782043 | 0.76 | PKM (0.45) | HTTMEN1KMT2ANPSR1MAPT | |
| SCHEMBL14073643 | 0.76 | ATM (0.46) | HTTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4843147 | 0.75 | TAAR1 (0.52) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6712518 | 0.75 | MAPT (0.63) | HTTMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11261156 | 0.75 | NPC1 (0.52) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10614890 | 0.74 | MAPT (0.58) | HTTMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4951837 | 0.73 | ALDH1A1 (0.73) | MEN1KMT2AMAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429278-B2 | N-alkyleheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'ORÉAL (FR) | 2008-09-30 | — | — | US | disclosed |
| US-7429278-B2 | N-alkyleheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'ORÉAL (FR) | 2008-09-30 | — | — | US | disclosed |
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | L'OREAL S.A. | 2008-03-20 | — | — | US | disclosed |
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | L'OREAL S.A. | 2008-03-20 | — | — | US | disclosed |
| US-20060005320-A1 | N-alkylheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
| EP-1589012-A2 | N-alkylheteroaryl secondary para-phenyldiamine, dyeing composition containing the same, process for making it and uses thereof | L'OREAL (FR) | 2005-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | KRT18, CDC73, PRKDC | THRB 4254/4885HTT 2477/4885MEN1 2486/4885 |
| US-20060005320-A1 | N-alkylheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | KRT18, CDC73, PRKDC | THRB 4254/4885HTT 2477/4885MEN1 2486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.