Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.49 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | USP8 | P40818 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | IDH2 | P48735 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775594 | 0.93 | SLC20A2 (0.51) | SLC20A2SLC20A1USP2USP8PLAU | |
| SCHEMBL6378305 | 0.88 | GAA (0.43) | SLC20A2SLC20A1USP2USP8PLAU | |
| SCHEMBL4780564 | 0.88 | AXL (0.47) | SLC40A1MEN1GAAKMT2AAXL | |
| SCHEMBL30304724 | 0.88 | AXL (0.47) | SLC40A1MEN1GAAKMT2AAXL | |
| SCHEMBL31478890 | 0.86 | MEN1 (0.55) | SLC40A1NR3C1PGRARESR2 | |
| SCHEMBL4726823 | 0.86 | MEN1 (0.55) | SLC40A1NR3C1PGRARESR2 | |
| SCHEMBL18051609 | 0.84 | NR1H4 (0.44) | SLC20A2SLC20A1PLAUPLATGAA | |
| SCHEMBL4777459 | 0.83 | LMNA (0.45) | SLC40A1MEN1GAAKMT2ALMNA | |
| SCHEMBL4779284 | 0.82 | AXL (0.51) | SLC20A2SLC20A1USP2USP8PLAU | |
| SCHEMBL5565243 | 0.80 | MEN1 (0.52) | SLC20A2SLC20A1USP2USP8SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008374-A2 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |