Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | RORB | Q92753 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703940 | 0.89 | FABP4 (0.70) | FABP4NR1H2NR1H3LMNAGAA | |
| SCHEMBL530568 | 0.86 | FABP4 (0.58) | FABP4NR1H2NR1H3LMNAGAA | |
| SCHEMBL30339795 | 0.86 | FABP4 (0.58) | FABP4NR1H2NR1H3LMNAGAA | |
| SCHEMBL31304715 | 0.86 | FABP4 (0.58) | FABP4NR1H2NR1H3LMNAGAA | |
| Hydrochloric Acid SCHEMBL28812647 | 0.85 | FABP4 (0.57) | FABP4NR1H2NR1H3LMNAGAA | |
| SCHEMBL2597832 | 0.80 | FABP4 (0.53) | FABP4NR1H2NR1H3LMNAALDH1A1 | |
| SCHEMBL746794 | 0.78 | LMNA (0.64) | LMNAGAAKCNK3KCNK9PTGS1 | |
| SCHEMBL11459852 | 0.77 | RORC (0.51) | FABP4LMNAGAARORCRORB | |
| SCHEMBL28553901 | 0.77 | FABP4 (1.00) | FABP4TAS2R14MEN1ALDH1A1KMT2A | |
| SCHEMBL28815055 | 0.77 | LMNA (0.62) | LMNAGAAKCNK3KCNK9PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345079-B2 | Treatment of disorder related to low cyclic GMP levels | YUNG SHIN PHARMACEUTICALS INDUSTRIAL CO., LTD (TW) | 2008-03-18 | — | — | US | disclosed |
| US-20030220385-A1 | Treatment of disorder related to low cyclic GMP levels | YUNG SHIN PHARMACEUTICALS INDUSTRIAL CO., LT.D (TW) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220385-A1 | Treatment of disorder related to low cyclic GMP levels | PDE7A, PDE2A, PDE4A | FABP4 2875/4885NR1H2 1302/4885NR1H3 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.