SCHEMBL2597832

SCHEMBL2597832

FC(F)(F)c1cccc(C(F)(F)F)c1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.53
KIF11 P52732 2/20 0.46
ESR1 P03372 1/20 0.46
PDK2 Q15119 1/20 0.44
NR1H2 P55055 2/20 0.43
NR1H3 Q13133 2/20 0.43
ALDH1A1 P00352 4/20 0.42
HSD11B1 P28845 1/20 0.42
TSHR P16473 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
ACHE P22303 1/20 0.41
ENPP1 P22413 1/20 0.41
POLB P06746 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
SCN9A Q15858 1/20 0.39
MCL1 Q07820 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28222652 0.95 KIF11 (0.54) FABP4KIF11ESR1PDK2NR1H2
SCHEMBL2293216 0.88 FABP4 (0.49) FABP4KIF11ESR1PDK2NR1H2
SCHEMBL3781200 0.87 FABP4 (0.47) FABP4KIF11ESR1PDK2NR1H2
SCHEMBL5123247 0.87 TRPA1 (0.49) FABP4KIF11ESR1PDK2NR1H2
SCHEMBL28022302 0.85 FABP4 (0.46) FABP4KIF11ESR1PDK2HSD11B1
SCHEMBL16428928 0.85 FABP4 (0.50) FABP4KIF11ESR1PDK2NR1H2
SCHEMBL12853969 0.81 PDK2 (0.46) FABP4KIF11ESR1PDK2ALDH1A1
SCHEMBL12853958 0.81 PDK2 (0.46) FABP4KIF11ESR1PDK2ALDH1A1
SCHEMBL4846678 0.80 FABP4 (0.61) FABP4NR1H2NR1H3ALDH1A1LMNA
SCHEMBL6703940 0.80 FABP4 (0.70) FABP4NR1H2NR1H3ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685786-B Polyimide film and preparation method and application thereof 中国科学院化学研究所 2023-05-02 CN claimed
CN-113150545-B Polymer film containing nano fullerene and preparation method thereof 北京市科学技术研究院分析测试研究所(北京市理化分析测试中心) 2022-11-15 CN claimed
CN-114685986-A Polyimide film and preparation method and application thereof 中国科学院化学研究所 2022-07-01 CN claimed
CN-114685786-A Polyimide film and preparation method and application thereof 中国科学院化学研究所 2022-07-01 CN claimed
CN-114685986-B Polyimide film with good heat resistance, transparency and heat conductivity 中国科学院化学研究所 2023-06-06 CN disclosed
CN-114685786-B Polyimide film and preparation method and application thereof 中国科学院化学研究所 2023-05-02 CN disclosed
CN-114685986-A Polyimide film and preparation method and application thereof 中国科学院化学研究所 2022-07-01 CN disclosed
CN-114685786-A Polyimide film and preparation method and application thereof 中国科学院化学研究所 2022-07-01 CN disclosed
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US disclosed
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US disclosed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 US disclosed
WO-2014104557-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT 한국과학기술원 (KR) 2014-07-03 WO disclosed
EP-2571860-A1 2-PHENYL BENZOYLAMIDES Pfizer Inc (US) 2013-03-27 EP disclosed
WO-2011145022-A1 2-PHENYL BENZOYLAMIDES PFIZER INC. (US) 2011-11-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 FABP4 3399/4885KIF11 1854/4885ESR1 1788/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 FABP4 2640/4885KIF11 2277/4885ESR1 1587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.