SCHEMBL4847386

SCHEMBL4847386

Nc1ccc(Oc2c(C(F)(F)F)cc(C(F)C(F)(F)C(F)(F)F)cc2C(F)(F)F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
GAA P10253 2/20 0.38
POLB P06746 2/20 0.38
GLA P06280 1/20 0.38
ALDH1A1 P00352 6/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MITF O75030 1/20 0.34
GFER P55789 1/20 0.34
NLRP1 Q9C000 1/20 0.34
NOD2 Q9HC29 1/20 0.34
KIF11 P52732 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14223513 0.83 TSHR (0.48) TSHRGAAPOLBGLAALDH1A1
SCHEMBL4854975 0.83 ALDH1A1 (0.40) TSHRGAAPOLBALDH1A1TDP1
SCHEMBL3143397 0.81 TSHR (0.39) TSHRGAAPOLBGLAALDH1A1
SCHEMBL3146062 0.80 ALDH1A1 (0.50) TSHRGAAPOLBALDH1A1TDP1
SCHEMBL8143487 0.79 TSHR (0.47) TSHRGAAPOLBGLAALDH1A1
SCHEMBL29962772 0.78 ALDH1A1 (0.52) TSHRGAAPOLBGLAALDH1A1
SCHEMBL8405569 0.77 ALDH1A1 (0.36) TSHRGAAPOLBGLAALDH1A1
SCHEMBL4847389 0.77 ALDH1A1 (0.36) TSHRGAAPOLBGLAALDH1A1
SCHEMBL650782 0.76 ALDH1A1 (0.41) TSHRGAAPOLBGLAALDH1A1
SCHEMBL8364552 0.75 ALDH1A1 (0.54) TSHRGAAALDH1A1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874420-A Resin film, metal-clad laminate, and method for producing same 日铁化学材料株式会社 2021-12-31 CN disclosed
US-20200071569-A1 METHOD OF PRODUCING JOINED BODY, COMPOSITION FOR TRANSIENT LIQUID PHASE SINTERING, SINTERED BODY, AND JOINED BODY HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-03-05 US disclosed
US-7457498-B2 Optical waveguide structure HITACHI CHEMICAL COMPANY, LTD. (JP) 2008-11-25 US disclosed
US-7450803-B2 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-20070086705-A1 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-04-19 US disclosed
US-20070031087-A1 Optical waveguide structure HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-02-08 US disclosed
US-5856065-A BLEND CONTAINING PHOTOINITIATOR AND ORGANOSILICON COMPOUND OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-01-05 US disclosed
US-5572619-A Polimide optical waveguide NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1996-11-05 US disclosed