SCHEMBL4854975

SCHEMBL4854975

Cc1cc(C(F)C(F)(F)C(F)(F)F)cc(C)c1Oc1ccc(N)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
TEAD4 Q15561 1/20 0.39
MAPT P10636 5/20 0.38
TDP1 Q9NUW8 4/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 2/20 0.36
TSHR P16473 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
MAPK1 P28482 2/20 0.36
HPGD P15428 1/20 0.36
AR P10275 2/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MITF O75030 1/20 0.34
GAA P10253 1/20 0.34
GFER P55789 1/20 0.34
NLRP1 Q9C000 1/20 0.34
NOD2 Q9HC29 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4847386 0.83 TSHR (0.38) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL3146062 0.80 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL8405668 0.78 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL4854970 0.78 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL27939453 0.78 HSP90AA1 (0.45) ALDH1A1TDP1MAPK1HPGDAR
SCHEMBL31343904 0.78 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL8502827 0.78 KDM4E (0.44) ALDH1A1MAPTTDP1CYP3A4GAA
SCHEMBL648768 0.77 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL2514220 0.77 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL8364552 0.75 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891570-A Polyamic acid, polyimide, metal-clad laminate, and circuit board 日铁化学材料株式会社 2023-10-17 CN disclosed
CN-113874420-B Resin film and metal-clad laminate 日铁化学材料株式会社 2023-09-26 CN disclosed
CN-116367413-A Metal-clad laminate and circuit board 日铁化学材料株式会社 2023-06-30 CN disclosed
CN-116353168-A Resin laminate, circuit board, electronic component, and electronic device 日铁化学材料株式会社 2023-06-30 CN disclosed
CN-113874420-A Resin film, metal-clad laminate, and method for producing same 日铁化学材料株式会社 2021-12-31 CN disclosed
US-20200071569-A1 METHOD OF PRODUCING JOINED BODY, COMPOSITION FOR TRANSIENT LIQUID PHASE SINTERING, SINTERED BODY, AND JOINED BODY HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-03-05 US disclosed
US-20200063008-A1 COMPOSITION, ADHESIVE, SINTERED BODY, JOINED BODY, AND METHOD OF PRODUCING JOINED BODY HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-02-27 US disclosed
US-7450803-B2 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-20070086705-A1 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-04-19 US disclosed
US-5856065-A BLEND CONTAINING PHOTOINITIATOR AND ORGANOSILICON COMPOUND OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-01-05 US disclosed