Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.67 |
| ▸ | PPID | Q08752 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015490 | 0.95 | LTA4H (0.66) | LTA4HPPIDSIGMAR1ALOX5KMT2A | |
| SCHEMBL7415640 | 0.89 | LTA4H (0.63) | LTA4HPPIDSIGMAR1ALOX5KMT2A | |
| Hydrochloric Acid SCHEMBL27717592 | 0.88 | LTA4H (0.61) | LTA4HPPIDSIGMAR1ALOX5KMT2A | |
| SCHEMBL7930242 | 0.88 | LTA4H (0.58) | LTA4HPPIDSIGMAR1ALOX5KMT2A | |
| SCHEMBL5695106 | 0.86 | SIGMAR1 (0.58) | LTA4HSIGMAR1 | |
| SCHEMBL16761953 | 0.86 | LTA4H (0.66) | LTA4HSIGMAR1ALOX5 | |
| SCHEMBL6136275 | 0.82 | LTA4H (0.67) | LTA4HSIGMAR1ALOX5 | |
| SCHEMBL12559711 | 0.82 | PPID (0.64) | LTA4HPPIDKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9543983 | 0.81 | SIGMAR1 (0.58) | LTA4HSIGMAR1KMT2AHPGD | |
| SCHEMBL9369849 | 0.80 | GAA (0.65) | PPIDALOX5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446204-B2 | Amino substituted aryloxybenzylpiperidine derivatives | H. LUNDBECK A/S (DK) | 2008-11-04 | — | — | US | disclosed |
| EP-1804796-A2 | AMINO SUBSTITUTED ARYLOXYBENZYLPIPERIDINE DERIVATIVES | H.Lundbeck A/S (DK) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006041636-A2 | AMINO SUBSTITUTED ARYLOXYBENZYLPIPERIDINE DERIVATIVES | H.LUNDBECK A/S (DK) | 2006-04-20 | — | — | WO | disclosed |
| US-20060079522-A1 | Amino substituted aryloxybenzylpiperidine derivatives | H. LUNDBECK A/S (DK) | 2006-04-13 | — | — | US | disclosed |
| US-20060079524-A1 | Amino substituted aryloxybenzylpiperidine derivatives | H. LUNDBECK A/S | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079524-A1 | Amino substituted aryloxybenzylpiperidine derivatives | MCHR1, MCHR2, MC4R | LTA4H 1531/4885PPID 2541/4885SIGMAR1 67/4885 |
| US-20060079522-A1 | Amino substituted aryloxybenzylpiperidine derivatives | MCHR1, MCHR2, MC4R | LTA4H 1718/4885PPID 2421/4885SIGMAR1 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.