Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695106 | 0.95 | SIGMAR1 (0.58) | SIGMAR1L3MBTL1S1PR1S1PR3LTA4H | |
| SCHEMBL7246282 | 0.90 | CA12 (0.56) | SIGMAR1KMT2ACYP2D6NPC1RAB9A | |
| SCHEMBL8015490 | 0.86 | LTA4H (0.66) | SIGMAR1KMT2APOLBHPGDLTA4H | |
| SCHEMBL19438565 | 0.85 | SIGMAR1 (0.61) | SIGMAR1L3MBTL1KMT2ADRD2DRD4 | |
| SCHEMBL7138314 | 0.84 | POLB (0.54) | SIGMAR1L3MBTL1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL19438777 | 0.84 | SIGMAR1 (0.59) | SIGMAR1L3MBTL1CA12CA7CA9 | |
| Hydrochloric Acid SCHEMBL19438468 | 0.83 | SIGMAR1 (0.58) | SIGMAR1L3MBTL1CA12CA7CA9 | |
| SCHEMBL4932073 | 0.83 | SIGMAR1 (0.62) | SIGMAR1CA12CA7CA9CA14 | |
| SCHEMBL158734 | 0.82 | SIGMAR1 (0.67) | SIGMAR1L3MBTL1NPC1RAB9AGAA | |
| SCHEMBL4847545 | 0.81 | LTA4H (0.67) | SIGMAR1KMT2AHPGDLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190119200-A1 | TERTIARY AMIDES AND METHOD OF USE | ABBVIE PHARMACEUTICAL TRADING (SHANGHAI) CO., LTD. (CN) | 2019-04-25 | — | — | US | disclosed |
| WO-2017177004-A1 | TERTIARY AMIDES AND METHOD OF USE | ABBVIE INC. (US) | 2017-10-12 | — | — | WO | disclosed |
| CN-103228621-B | Labeling reagent, and method for sequencing and quantifying polypeptide and protein using same | 浦项工科大学校产学协力团 | 2016-06-15 | — | — | CN | disclosed |
| US-8809012-B2 | Labeling agent and methods for simultaneous sequencing and quantification of multiple peptides and proteins using the same | Postach Academy-Industry Foundation (KR) | 2014-08-19 | — | — | US | disclosed |
| CN-103228621-A | Labeling reagent, and amino acid sequence and protein multiplex quantitative simultaneous analysis method using same | POSTECH ACAD IND FOUND | 2013-07-31 | — | — | CN | disclosed |
| US-20130183704-A1 | Labeling Agent and Methods for Simultaneous Sequencing and Quantification of Multiple Peptides and Proteins Using the Same | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2013-07-18 | — | — | US | disclosed |
| EP-2610243-A2 | LABELING AGENT AND AMINO ACID SEQUENCE USING SAME, AND METHOD FOR PERFORMING SIMULTANEOUS QUANTITATIVE ANALYSIS OF MULTIPLE PROTEINS | Postech Academy-industry Foundation (KR) | 2013-07-03 | — | — | EP | disclosed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130183704-A1 | Labeling Agent and Methods for Simultaneous Sequencing and Quantification of Multiple Peptides and Proteins Using the Same | YWHAQ, IAPP, RPS27A | SIGMAR1 4628/4885L3MBTL1 1405/4885KMT2A 946/4885 |
| US-20190119200-A1 | TERTIARY AMIDES AND METHOD OF USE | LPAR1, LPAR3, LPAR2 | SIGMAR1 233/4885L3MBTL1 604/4885KMT2A 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.