Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL1822236 | 0.81 | ALDH1A1 (0.61) | LMNAALDH1A1TSHRGAADGAT1 | |
| Methyl Alcohol SCHEMBL6261246 | 0.81 | — | — | |
| SCHEMBL49039 | 0.80 | — | — | |
| Acetone SCHEMBL11778591 | 0.79 | LMNA (0.43) | LMNAALDH1A1TSHRGAADGAT1 | |
| SCHEMBL298347 | 0.78 | — | — | |
| SCHEMBL29989468 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27895817 | 0.76 | — | — | |
| Hypophosphorous Acid SCHEMBL11214397 | 0.76 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL19859132 | 0.76 | TSHR (0.67) | LMNAALDH1A1TSHR | |
| Cyclohexane SCHEMBL2480141 | 0.73 | ALDH1A1 (0.50) | LMNAALDH1A1TSHRDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200516-A | Synthesis of sugars from substituted and unsubstituted arene diols | VIRGINIA TECH INTELLECTUAL PROPERTIES (US) | 1993-04-06 | — | — | US | claimed |
| US-20200281944-A1 | Combinations Of Lanosterol Or 25-Hydroxycholesterol Including Derivatives Thereof Useful In The Treatment Of Lens Disorders | PIRAEE MAHMOOD (CA) | 2020-09-10 | — | — | US | disclosed |
| CN-107207515-B | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-106377540-A | Bifunctional compounds binding to adenosine A2A receptors and adenosine transporters for the prevention and treatment of neurodegenerative diseases | 中央研究院 | 2017-02-08 | — | — | CN | disclosed |
| US-7332476-B2 | Pyridyl substituted ketolide antibiotics | NOVARTIS AG (CH) | 2008-02-19 | — | — | US | disclosed |
| WO-2008009138-A1 | CHLOROGENIC ACID DERIVATIVES AND THEIR USE AS ANTI-FUNGAL AGENTS | GENESIS GROUP INC. (CA) | 2008-01-24 | — | — | WO | disclosed |
| EP-1704161-A1 | HELIX 12 DIRECTED STEROIDAL PHARMACEUTICAL PRODUCTS | Endorecherche, Inc. (CA) | 2006-09-27 | — | — | EP | disclosed |
| EP-1618119-A2 | PYRIDYL SUBSTITUTED KETOLIDE ANTIBIOTICS | CHIRON CORPORATION (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1572710-A2 | ANTIVIRAL NUCLEOSIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| WO-2005066194-A1 | HELIX 12 DIRECTED STEROIDAL PHARMACEUTICAL PRODUCTS | ENDORECHERCHE, INC. (CA) | 2005-07-21 | — | — | WO | disclosed |
| US-6054478-A | PREVENTION OR CURE OF FUNGAL DISEASES IN HUMANS AND ANIMALS;PREPARED BY BIIOTRANSFORMATION | GLAXO WELLCOME S.A. (ES) | 2000-04-25 | — | — | US | disclosed |
| US-5952334-A | SORDARIN DERIVATIVES; FUNGICIDES | GLAXO WELLCOME S.A. (ES) | 1999-09-14 | — | — | US | disclosed |
| EP-0753001-B1 | ANTIFUNGAL SORDARIDIN DERIVATIVES | GLAXO WELLCOME SA (ES) | 1999-09-08 | — | — | EP | disclosed |
| EP-0791007-B1 | ANTIFUNGAL SORDARIDIN DERIVATIVES | GLAXO WELLCOME SA (ES) | 1999-08-11 | — | — | EP | disclosed |
| US-5854280-A | Antifungal sordaridin derivatives | GLAXO WELLCOME S.A. (ES) | 1998-12-29 | — | — | US | disclosed |
| EP-0791007-A1 | ANTIFUNGAL SORDARIDIN DERIVATIVES | Glaxo Wellcome S.A. (ES) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014327-A1 | ANTIFUNGAL SORDARIDIN DERIVATIVES | GLAXO WELLCOME S.A. (ES) | 1996-05-17 | — | — | WO | disclosed |
| EP-0711783-A1 | Antifungal Sordarin derivatives | GLAXO, S.A. (ES) | 1996-05-15 | — | — | EP | disclosed |
| US-5173510-A | Anticholesterol agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| US-5053426-A | Enzyme inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281944-A1 | Combinations Of Lanosterol Or 25-Hydroxycholesterol Including Derivatives Thereof Useful In The Treatment Of Lens Disorders | CYP46A1, LSS, CYP27A1 | LMNA 159/4885ALDH1A1 3533/4885TSHR 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.