Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.71 |
| ▸ | HPGD | P15428 | 10/20 | 0.71 |
| ▸ | RAB9A | P51151 | 9/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.71 |
| ▸ | RELA | Q04206 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.71 |
| ▸ | STAT1 | P42224 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | GFER | P55789 | 1/20 | 0.71 |
| ▸ | GLA | P06280 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182250 | 0.78 | NPC1 (0.57) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL8964867 | 0.76 | ALDH1A1 (0.61) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL19629030 | 0.76 | ALDH1A1 (0.61) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1507971 | 0.76 | APP (0.63) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL13862728 | 0.76 | PIK3CA (0.65) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1983093 | 0.76 | PIK3CA (0.65) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL5708075 | 0.75 | NPC1 (0.63) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL16363763 | 0.75 | NPC1 (0.63) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL18898372 | 0.75 | ALDH1A1 (0.60) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL2174585 | 0.75 | NPC1 (0.66) | NPC1KDM4EALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378240-B2 | Synthesis and evaluation of new cyanine dyes as minor groove of [POLY(dA-dT)]2 binders | LIGHT UP TECHNOLOGIES AB (SE) | 2008-05-27 | — | — | US | disclosed |
| US-7378240-B2 | Synthesis and evaluation of new cyanine dyes as minor groove of [POLY(dA-dT)]2 binders | LIGHT UP TECHNOLOGIES AB (SE) | 2008-05-27 | — | — | US | disclosed |
| US-7378240-B2 | Synthesis and evaluation of new cyanine dyes as minor groove of [POLY(dA-dT)]2 binders | LIGHT UP TECHNOLOGIES AB (SE) | 2008-05-27 | — | — | US | disclosed |
| EP-1390433-B1 | SYNTHESIS AND EVALUATION OF NEW CYANINE DYES AS MINOR GROOVE OF POLY(DA-DT)] 2 BINDERS | LIGHT UP TECHNOLOGIES AB (SE) | 2005-02-16 | — | — | EP | disclosed |
| US-20040132046-A1 | Synthesis and evaluation of new cyanine dyes as minor groove of [POLY (dA-dT)]2 binders | LIGHT UP TECHNOLOGIES AB (SE) | 2004-07-08 | — | — | US | disclosed |
| EP-1390433-A1 | SYNTHESIS AND EVALUATION OF NEW CYANINE DYES AS MINOR GROOVE OF POLY(DA-DT)] 2 BINDERS | Light Up Technologies AB (SE) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002090443-A1 | SYNTHESIS AND EVALUATION OF NEW CYANINE DYES AS MINOR GROOVE OF [POLY(DA-DT)]2 BINDERS | LIGHT UP TECHNOLOGIES AB (SE) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132046-A1 | Synthesis and evaluation of new cyanine dyes as minor groove of [POLY (dA-dT)]2 binders | DRD4, FUT4, DRD1 | NPC1 3194/4885KDM4E 3317/4885ALDH1A1 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.