Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | HPGD | P15428 | 9/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | STAT1 | P42224 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18941934 | 0.89 | ALDH1A1 (0.54) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL21984002 | 0.84 | RAB9A (0.51) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL21984499 | 0.83 | RAB9A (0.50) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18389311 | 0.82 | KDM4E (0.54) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19164514 | 0.81 | KDM4E (0.53) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL447980 | 0.81 | APP (0.55) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL26189371 | 0.79 | RIPK1 (0.53) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL21466951 | 0.78 | ALDH1A1 (0.59) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3493900 | 0.77 | APP (0.52) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL2174585 | 0.76 | NPC1 (0.66) | ALDH1A1NPC1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220087917-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2022-03-24 | — | — | US | disclosed |
| US-10434052-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | SAMUMED, LLC (US) | 2019-10-08 | — | — | US | disclosed |
| US-10040759-B2 | Substituted azetidinyl compounds as GlyT1 inhibitors | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2018-08-07 | — | — | US | disclosed |
| US-20180193244-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2018-07-12 | — | — | US | disclosed |
| US-9974865-B2 | Antibody drug conjugates (ADC) that bind to FLT3 proteins | AGENSYS, INC. (US) | 2018-05-22 | — | — | US | disclosed |
| US-20170334846-A1 | SUBSTITUTED AZETIDINYL COMPOUNDS AS GLYT1 INHIBITORS | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180193244-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | GLA, DGKG, DGKA | ALDH1A1 985/4885NPC1 4073/4885KDM4E 656/4885 |
| US-20220087917-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | GLA, DGKG, DGKA | ALDH1A1 985/4885NPC1 4073/4885KDM4E 656/4885 |
| US-10040759-B2 | Substituted azetidinyl compounds as GlyT1 inhibitors | GLRA1, AGXT, B4GALT1 | ALDH1A1 308/4885NPC1 217/4885KDM4E 2654/4885 |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | DGKG, DGKA, DNER | ALDH1A1 1485/4885NPC1 3947/4885KDM4E 417/4885 |
| US-20170334846-A1 | SUBSTITUTED AZETIDINYL COMPOUNDS AS GLYT1 INHIBITORS | GLRA1, AGXT, B4GALT1 | ALDH1A1 308/4885NPC1 217/4885KDM4E 2654/4885 |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | GSK3A, GSK3B, WNT1 | ALDH1A1 1093/4885NPC1 1450/4885KDM4E 3614/4885 |
| US-10434052-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | GLA, DGKA, DGKG | ALDH1A1 1129/4885NPC1 4077/4885KDM4E 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.