Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280884 | 0.92 | BCHE (0.46) | CAPN1BCHEACHECTSLCTSB | |
| SCHEMBL4849986 | 0.92 | BCHE (0.46) | CAPN1BCHEACHECTSLCTSB | |
| SCHEMBL4849921 | 0.91 | BCHE (0.45) | BCHEACHEDPP4PTPN1LMNA | |
| SCHEMBL4856242 | 0.91 | BCHE (0.45) | BCHEACHECTSLCTSBLMNA | |
| SCHEMBL4853736 | 0.91 | BCHE (0.52) | BCHEACHELMNATNFRSF1AMAPT | |
| SCHEMBL6386830 | 0.90 | ABCG2 (0.52) | BCHEACHEDPP4PTPN1LMNA | |
| SCHEMBL4853514 | 0.89 | NR1H4 (0.47) | CAPN1BCHEACHEDPP4CHRNA7 | |
| SCHEMBL4848121 | 0.88 | BCHE (0.55) | CAPN1BCHEACHECTSLCTSB | |
| SCHEMBL4847320 | 0.87 | SNCA (0.44) | BCHEACHEDPP4PTPN1TNFRSF1A | |
| SCHEMBL4847749 | 0.87 | ACHE (0.42) | BCHEACHELMNATNFRSF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227990-A1 | Aminoalkoxy-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2005-10-13 | — | — | US | claimed |
| US-7423181-B2 | in particular against bacterial and parasitic infections, fungi, and helminths; improved metabolic and physiochemical properties, bioavailability, solubility; 3-[4-(2-Dimethylamino-ethoxy)-2'-trifluoromethyl-biphenyl-3-yl]-1-(2-dimethylaminomethyl-phenyl)-propenone | LICA PHARMACEUTICALS A/S (DK) | 2008-09-09 | — | — | US | disclosed |
| US-20050227990-A1 | Aminoalkoxy-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2005-10-13 | — | — | US | disclosed |