Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854694 | 0.91 | MAPT (0.34) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL297785 | 0.88 | MAPT (0.41) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL10923832 | 0.84 | MAPT (0.47) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL1842052 | 0.84 | ALDH1A1 (0.44) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL522535 | 0.84 | MAPT (0.52) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL4848161 | 0.84 | MGAM (0.34) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL10917122 | 0.82 | MAPT (0.55) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL28854607 | 0.82 | MAPT (0.55) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL522729 | 0.82 | MAPT (0.55) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL8918315 | 0.82 | MAPT (0.38) | MAPTLMNAALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | disclosed |
| EP-1445641-B1 | OCULAR LENS | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20040201820-A1 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-14 | — | — | US | disclosed |
| US-20040198938-A1 | Monomers, polymers and ophthalmic lenses | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-07 | — | — | US | disclosed |
| EP-1445641-A1 | OCULAR LENS | Johnson & Johnson Vision Care, Inc. (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1424339-A1 | MONOMERS, POLYMERS AND OPHTHALMIC LENSES | Johson & Johnson Vision Care Inc. (US) | 2004-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198938-A1 | Monomers, polymers and ophthalmic lenses | LOXL1, CRYAA, UACA | MAPT 4050/4885LMNA 367/4885ALDH1A1 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.