SCHEMBL4849878

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1448564	0.88	ADRB1 (0.50)	ADRB1HTR6HTR3AHTR3EHTR3B
	SCHEMBL4258576	0.82	ADRB1 (0.50)	ADRB1HTR6HTR3AHTR3EHTR3B
	SCHEMBL8291557	0.82	ADRB1 (0.61)	ADRB1HTR6HTR3AHTR3EHTR3B
	Hydrochloric Acid SCHEMBL7836810	0.80	HTR1A (0.59)	ADRB1HTR6HTR3AHTR3EHTR3B
	SCHEMBL28291412	0.80	ADRB1 (0.59)	ADRB1HTR6HTR3AHTR3EHTR3B
	SCHEMBL1448468	0.80	ADRB1 (0.42)	ADRB1HTR6HTR3AHTR3EHTR3B
	SCHEMBL13811817	0.79	ADRB1 (0.44)	ADRB1HTR6HTR3AHTR3EHTR3B
	SCHEMBL4854190	0.78	DRD2 (0.54)	HTR6DRD2DRD3SIGMAR1LMNA
	SCHEMBL4856101	0.78	ADRB1 (0.56)	ADRB1HTR6HTR3AHTR3EHTR3B
	SCHEMBL4849498	0.78	ADRB1 (0.56)	ADRB1HTR6HTR3AHTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.