Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8250801 | 0.91 | ALDH1A1 (0.80) | ALDH1A1KDM4EL3MBTL1ATMTDP1 | |
| SCHEMBL5178089 | 0.89 | ALDH1A1 (0.77) | ALDH1A1KDM4EL3MBTL1ATMTDP1 | |
| SCHEMBL1946258 | 0.89 | L3MBTL1 (0.86) | ALDH1A1KDM4EL3MBTL1ATMTDP1 | |
| SCHEMBL3701693 | 0.88 | ALDH1A1 (0.83) | ALDH1A1KDM4EL3MBTL1ATMTDP1 | |
| Bromide SCHEMBL10462008 | 0.88 | L3MBTL1 (0.84) | ALDH1A1KDM4EL3MBTL1ATMTDP1 | |
| SCHEMBL10016602 | 0.87 | KDM4E (1.00) | ALDH1A1KDM4EL3MBTL1ATMTDP1 | |
| Hydrochloric Acid SCHEMBL8545412 | 0.87 | ALDH1A1 (0.81) | ALDH1A1KDM4EL3MBTL1ATMTDP1 | |
| SCHEMBL30364399 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KDM4EL3MBTL1ATMTDP1 | |
| Cadaverine Tartrate SCHEMBL27494555 | 0.85 | L3MBTL1 (0.76) | ALDH1A1KDM4EL3MBTL1ATMTDP1 | |
| SCHEMBL6093231 | 0.84 | KDM4E (0.77) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |