SCHEMBL4850200

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6021774	0.83	OPRD1 (0.34)	HTR1ASIGMAR1HTR7IDH1
	Hydrochloric Acid SCHEMBL4849935	0.83	DRD2 (0.41)	HTR1AHTR1DHTR1BSIGMAR1HTR7
	Hydrochloric Acid SCHEMBL4857320	0.83	OPRD1 (0.33)	HTR1ASIGMAR1HTR7IDH1
	Hydrochloric Acid SCHEMBL4857732	0.82	RORC (0.33)	NTSR1IDH1
	SCHEMBL4253297	0.82	DRD2 (0.39)	HTR1A
	Hydrochloric Acid SCHEMBL4851034	0.82	TMEM97 (0.39)	SIGMAR1
	SCHEMBL5024759	0.82	NTSR1 (0.38)	ADRB1HTR1AHTR1DHTR1BHTR3E
	SCHEMBL5024760	0.82	NTSR1 (0.38)	ADRB1HTR1AHTR1DHTR1BHTR3E
	SCHEMBL4856770	0.82	MAP4K4 (0.39)	NTSR1IDH1
	Hydrochloric Acid SCHEMBL4857009	0.81	DRD2 (0.39)	HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.