⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856244 | 0.93 | TSHR (0.40) | — | |
| SCHEMBL1799780 | 0.87 | DGKA (0.39) | — | |
| SCHEMBL12002781 | 0.86 | ALDH1A1 (0.45) | — | |
| SCHEMBL4847373 | 0.81 | DGKA (0.43) | — | |
| SCHEMBL8598315 | 0.80 | ALDH1A1 (0.50) | — | |
| SCHEMBL8195502 | 0.79 | — | — | |
| SCHEMBL813361 | 0.79 | ADRA2A (0.54) | — | |
| SCHEMBL813498 | 0.79 | MGAM (0.50) | — | |
| SCHEMBL8897523 | 0.78 | DGKA (0.50) | — | |
| SCHEMBL181426 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | claimed |
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | claimed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | claimed |
| EP-0684287-A1 | Water insoluble red monoazo dyes, their preparation and the use thereof | HOECHST MITSUBISHI KASEI CO., LTD. (JP) | 1995-11-29 | — | — | EP | claimed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | claimed |
| US-5283326-A | Coupling azo and cyanine dyes; colorfastness, heat resistance | SANDOZ AG (CH) | 1994-02-01 | — | — | US | claimed |
| US-4960873-A | 3-pyridylisothiazoleazo compounds useful as disperse dyes | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | claimed |
| US-4837269-A | FIBER-REACTIVE DISAZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 1989-06-06 | — | — | US | claimed |
| US-4751288-A | COLORFASTNESS | BASF AKTIENGESELLSCHAFT (DE) | 1988-06-14 | — | — | US | claimed |
| US-4619992-A | IMPROVED COLORFASTNESS | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-28 | — | — | US | claimed |
| US-4542207-A | Heterocyclic monoazo dyes for polyester fibers | RESEARCH ASSOCIATION OF SYNTHETIC DYESTUFFS (JP) | 1985-09-17 | — | — | US | claimed |
| US-4496480-A | Isothiazolazo dyes having coupling components which are free from unsaturated aliphatic radicals | BASF AKTIENGESELLSCHAFT (DE) | 1985-01-29 | — | — | US | claimed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | claimed |
| CN-102574206-B | Metal nanoparticle-containing composite, dispersion thereof, and method for producing same | DAINIPPON INK & CHEMICALS CORP | 2014-06-04 | — | — | CN | disclosed |
| CN-102574206-A | Metal nanoparticle-containing composite, dispersion thereof, and method for producing same | DAINIPPON INK & CHEMICALS CORP | 2012-07-11 | — | — | CN | disclosed |
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-4398913-A | ALKALINE PASTES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |
| EP-0045354-A1 | A method of dyeing and printing hydrophobic fibrous materials, and azo dyestuffs suitable therefor | CASSELLA Aktiengesellschaft (DE) | 1982-02-10 | — | — | EP | disclosed |
| US-4252718-A | Continuous azo coupling process | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-02-24 | — | — | US | disclosed |
| US-4211696-A | Disperse monoazo dyestuffs derived from 3,5-dinitro-2-amino thiophene as disazo component and an arylamine coupling component | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-07-08 | — | — | US | disclosed |