SCHEMBL4852020

SCHEMBL4852020

CCN(N)c1ccccc1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALOX15 P16050 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
CA12 O43570 1/20 0.38
GMNN O75496 1/20 0.38
ALDH1A1 P00352 1/20 0.38
EGFR P00533 1/20 0.38
CA2 P00918 1/20 0.38
LMNA P02545 1/20 0.38
FYN P06241 1/20 0.38
POLB P06746 1/20 0.38
CA3 P07451 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
MMP9 P14780 1/20 0.38
HPGD P15428 1/20 0.38
NFKB1 P19838 1/20 0.38
CA4 P22748 1/20 0.38
APEX1 P27695 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL6528421 0.91 ESR1 (0.41) CA2ESR1
SCHEMBL29137166 0.83 HTR1A (0.46) TSHRHTR1AESR1AOC3
SCHEMBL29137135 0.80 HTR1A (0.40) TSHRKDM4EALDH1A1LMNAPOLB
SCHEMBL29137147 0.79 ALDH1A1 (0.40) TSHRALOX15KDM4ENPC1ALDH1A1
SCHEMBL29137126 0.77 ALDH1A1 (0.42) TSHRALOX15KDM4ENPC1ALDH1A1
SCHEMBL29137160 0.77 ALDH1A1 (0.42) TSHRALOX15KDM4ENPC1ALDH1A1
SCHEMBL29137121 0.77 ALDH1A1 (0.42) TSHRALOX15KDM4ENPC1ALDH1A1
SCHEMBL29137139 0.77 ALDH1A1 (0.42) TSHRALOX15KDM4ENPC1ALDH1A1
SCHEMBL29137141 0.77 ALDH1A1 (0.42) TSHRALOX15KDM4ENPC1ALDH1A1
SCHEMBL10333062 0.77 ALDH1A1 (0.42) TSHRALOX15KDM4ENPC1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113574041-B Bisphenol production method and polycarbonate resin production method 三菱化学株式会社 2023-10-13 CN disclosed
US-7455697-B2 (3,5-diaminophenyl)(2,4-dihydroxyphenyl)methanone and the acid adducts thereof, method for their preparation and use of these compounds for dyeing fibers WELLA AG (DE) 2008-11-25 US disclosed
US-20070180629-A1 (3,5-Diaminophenyl)(2,4-dihydroxyphenyl)methanone and the acid adducts thereof, method for their preparation and use of these compounds for dyeing fibers Wella GmbH (DE) 2007-08-09 US disclosed
US-6180818-B1 COMPOUND PROVIDING IMPROVED STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2001-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070180629-A1 (3,5-Diaminophenyl)(2,4-dihydroxyphenyl)methanone and the acid adducts thereof, method for their preparation and use of these compounds for dyeing fibers GRHPR, MB, COX5B TSHR 2671/4885ALOX15 1729/4885KDM4E 2256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.