Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666013 | 0.84 | MCL1 (0.35) | MCL1 | |
| SCHEMBL4844097 | 0.78 | PSMB8 (0.38) | — | |
| SCHEMBL4850828 | 0.75 | — | — | |
| SCHEMBL193935 | 0.70 | GPR3 (0.37) | — | |
| SCHEMBL4852140 | 0.69 | AHR (0.32) | — | |
| SCHEMBL7386654 | 0.68 | PSMB8 (0.33) | — | |
| SCHEMBL4848591 | 0.64 | CYP3A4 (0.30) | — | |
| SCHEMBL3281839 | 0.63 | GPR3 (0.44) | MCL1 | |
| SCHEMBL266519 | 0.63 | CYP2A6 (0.53) | MCL1 | |
| SCHEMBL2382103 | 0.60 | PDK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323488-B2 | Chromogenic enzyme substrates | BURTON MICHAEL | 2008-01-29 | — | — | US | claimed |
| EP-1436411-B1 | CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2005-12-14 | — | — | EP | claimed |
| US-20050124556-A1 | Chromogenic enzyme substrates | BURTON MICHAEL (GB) | 2005-06-09 | — | — | US | claimed |
| EP-1436411-A2 | CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | Burton, Michael (GB) | 2004-07-14 | — | — | EP | claimed |
| WO-2003035896-A2 | CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2003-05-01 | — | — | WO | claimed |
| US-7323488-B2 | Chromogenic enzyme substrates | BURTON MICHAEL | 2008-01-29 | — | — | US | disclosed |
| EP-1436411-B1 | CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2005-12-14 | — | — | EP | disclosed |
| US-20050124556-A1 | Chromogenic enzyme substrates | BURTON MICHAEL (GB) | 2005-06-09 | — | — | US | disclosed |
| EP-1436411-A2 | CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | Burton, Michael (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003035896-A2 | CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124556-A1 | Chromogenic enzyme substrates | DCXR, MGAM, IDE | MCL1 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.